2′,3′-O-Isopropylideneuridine Chemical Properties

Melting point:

163-166 °C

Boiling point:

426.76°C (rough estimate)

Density 

1.2932 (rough estimate)

refractive index 

1.5460 (estimate)

storage temp. 

-20°C

solubility 

Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)

form 

Fine Crystalline Powder or Needles

pka

9.25±0.10(Predicted)

color 

White

BRN 

32671

InChI

InChI=1S/C12H16N2O6/c1-12(2)19-8-6(5-15)18-10(9(8)20-12)14-4-3-7(16)13-11(14)17/h3-4,6,8-10,15H,5H2,1-2H3,(H,13,16,17)/t6-,8-,9-,10-/m1/s1

InChIKey

GFDUSNQQMOENLR-PEBGCTIMSA-N

SMILES

OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@@H]2OC(O[C@H]12)(C)C

CAS DataBase Reference

362-43-6(CAS DataBase Reference)

Safety Information

Safety Statements 

24/25

WGK Germany 

3

HS Code 

29339900

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2′,3′-O-Isopropylideneuridine Usage And Synthesis

Description

2',3'-Isopropylideneuridine has been shown to inhibit binding of pestivirus inhibitors by monoclonal antibodies. 2',3'-Isopropylideneuridine was also found to inhibit the replication of human immunodeficiency virus (HIV) in tissue culture by binding to the viral RNA polymerase and inhibiting its activity, preventing viral replication.

Chemical Properties

White Needle-Like Crystals

Uses

2′,3′-O-Isopropylideneuridine is used in the chemical synthesis of N-benzoylated uridine derivatives and N³-substituted 2′,3′-O-isopropylideneuridines with central nervous system (CNS) depressant activity.

Uses

2',3'-O-Isopropylideneuridine can be used as a useful precursor for the preparation of nucleic acids.

2′,3′-O-Isopropylideneuridine(362-43-6)Related Product Information

• 2'-O-Methyluridine
• Uridine
• 2′,3′-O-Isopropylideneuridine
• 2,2-Dimethyl-1,3-dioxolane-4-methanol
• (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol
• 1,3-Dioxolane-4-methanol
• 3-Isopropoxypropylamine
• [(4S)-2,2-Dimethyl-1,3-dioxolan-4-yl]methanamine
• (S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol
• Torasemide
• N-ISOBUTYLUREA
• O-(4-NITROBENZYL)-N,N'-DIISOPROPYLISOUREA
• 1-(4-hydroxyphenyl)-3-propan-2-ylurea
• 4-[(ISOPROPYLCARBAMOYL)AMINO]BENZENEBORONIC ACID, PINACOL ESTER 98%4-(3-ISOPROPYLUREIDO)BENZENEBORONIC ACID, PINACOL ESTER
• 2',3'-O-ISOPROPYLIDENE-5-FLUOROURIDINE-13C,15N2
• 5-Chloro-2',3'-O-isopropylidene-D-uridine
• 1-(2'-HYDROXYETHYL)URACIL
• (2,2-DIMETHYL-[1,3]-DIOXOLAN-4-YL)-METHYLAMINE