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2,3-DIHYDROXYQUINOXALINE

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2,3-DIHYDROXYQUINOXALINE Basic information

Product Name:
2,3-DIHYDROXYQUINOXALINE
Synonyms:
  • 1,4-Dihydro-2,3-quinoxalinedione
  • 1,4-dihydro-3-quinoxalinedione
  • 2,3(1h,4h)-quinoxalinedione
  • 2,3-dihydroxy-quinoxalin
  • 2,3-Quinoxalinedione, 1,4-dihydro-
  • 2,3-Quinoxalinedione,1,4-dihydro-
  • Quinoxaline, 2,3-dihydroxy-
  • USAF ek-6232
CAS:
15804-19-0
MF:
C8H6N2O2
MW:
162.15
EINECS:
239-901-0
Product Categories:
  • Bioactive Small Molecules
  • Building Blocks
  • Cell Biology
  • Chemical Synthesis
  • DIG-DY
  • Heterocyclic Building Blocks
  • Quinolines, Quinazolines and derivatives
  • Quinoxalines
Mol File:
15804-19-0.mol
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2,3-DIHYDROXYQUINOXALINE Chemical Properties

Melting point:
>300 °C (lit.)
Boiling point:
288.82°C (rough estimate)
Density 
1.3264 (rough estimate)
refractive index 
1.5770 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
pka
10.66±0.20(Predicted)
form 
powder to crystaline
color 
White to Orange to Green
BRN 
136884
CAS DataBase Reference
15804-19-0(CAS DataBase Reference)
EPA Substance Registry System
2,3-Quinoxalinedione, 1,4-dihydro- (15804-19-0)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-37/38-41
Safety Statements 
22-24/25-39-26
WGK Germany 
3
RTECS 
VD2100000
TSCA 
Yes
HS Code 
29339900

MSDS

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2,3-DIHYDROXYQUINOXALINE Usage And Synthesis

Chemical Properties

off-white powder

Uses

2,3-Dihydroxyquinoxaline is a fluorescent reagent and it can be used for the determination of trace Pb(II) in vinegar.

Application

2,3-Dihydroxyquinoxaline can be used:
(1)  Basic chemical studies to determine the low-temperature x-ray molecular structure, reciprocal isomerism and spectroscopic properties of 2,3-Dihydroxyquinoxaline[1].
(2) Quinoline-5-carboxamide derivatives (Vq-Vu) and (VIa-Vu) were prepared by using methyl 2,3-diaminobenzoate as raw material[2].

General Description

2,3-Dihydroxyquinoxaline(dhq) undergoes electrophilic substitution reaction with sulphuric acid solution and potassium nitrate to form 2,3-dihydroxy-6-nitroquinoxaline. It reacts with Ru3(CO)12 in DMSO to give the Ru(CO)2(dhq)(DMSO) complex.

References

[1] SAIED M. SOLIMAN; Morsy A M A Y; J?rg Albering. Low temperature X-ray molecular structure, tautomerism and spectral properties of 2,3-dihydroxyquinoxaline[J]. Journal of Molecular Structure, 2013. DOI:10.1016/j.molstruc.2013.09.005.
[2] KEESARI SRINIVAS. Synthesis, Characterization, and Antibacterial Activity of Novel 2,3-Dihydroxyquinoxaline-5-сarboxamide Derivatives[J]. Russian Journal of Bioorganic Chemistry, 2023. DOI:10.1134/S106816202305014X.

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