Tetrafluoro-1-propanol Chemical Properties

Melting point:

-15°C

Boiling point:

109 °C

Density 

1.48 g/mL at 20 °C(lit.)

refractive index 

n20/D 1.321(lit.)

Flash point:

110 °F

storage temp. 

Sealed in dry,2-8°C

pka

13.05±0.10(Predicted)

form 

Liquid

color 

Clear colorless

Specific Gravity

1.481.471

Water Solubility 

Soluble in water.

Merck 

14,9206

BRN 

1738264

Stability:

Stable. Flammable. Incompatible with strong oxidizing agents, strong bases, sodium, potassium, acid chlorides, acid anhydrides.

CAS DataBase Reference

76-37-9(CAS DataBase Reference)

NIST Chemistry Reference

2,2,3,3-Tetrafluoro-1-propanol(76-37-9)

EPA Substance Registry System

1-Propanol, 2,2,3,3-tetrafluoro- (76-37-9)

Safety Information

Hazard Codes 

Xn,F,Xi

Risk Statements 

10-20-36-36/37/38

Safety Statements 

26-37/39-16-36/37-36

RIDADR 

UN 1986 3/PG 3

WGK Germany 

1

RTECS 

UB9400000

Hazard Note 

Flammable

TSCA 

T

HazardClass 

3

PackingGroup 

III

HS Code 

29051990

MSDS

• Language:English Provider:1H,1H,3H-Tetrafluoro-1-propanol
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Tetrafluoro-1-propanol Usage And Synthesis

Chemical Properties

colourless liquid

Uses

2,2,3,3-Tetrafluoro-1-propanol, is used as an essential fluorinated fine chemical, the main application of TFP is as a dye solvent in CD-R(W) and DVD-R(W) industry. It is also used in making textile treatment agent and pharmaceuticals. This chemical is an ideal replacement for Freon 22 detergent.

General Description

2,2,3,3-Tetrafluoro-1-propanol (TFP) is extensively used as the solvent. Mineralization and defluoridation of TFP by UV oxidation in a novel three-phase fluidized bed reactor was reported. Desorption of activated carbon loaded with TFP by supercritical carbon dioxide in a rotating packed bed was investigated.

Purification Methods

Tetrafluoro-1-propanol (450mL) is added to a solution of 2.25g of NaHSO3 in 90mL of water, shaken vigorously and set aside for 24hours. The fraction distilling at or above 99o is refluxed for 4hours with 5-6g of KOH and rapidly distilled, followed by a final fractional distillation. [Kosower & Wu J Am Chem Soc 83 3142 1961.] Alternatively, shake the alcohol with alumina for 24hours, dry it overnight with anhydrous K2CO3 and distil it, taking the middle fraction (b 107-108o). [Beilstein 1 IV 2438.]

Tetrafluoro-1-propanol(76-37-9)Related Product Information

• Dimefluthrin
• Pentafluoro-1-propanol
• 1-Propanol
• Heptafluorobutyric anhydride
• Perfluoropropionic anhydride
• Methyl pentafluoropropionate
• 1H,1H-PENTADECAFLUORO-1-OCTANOL
• HEXAFLUOROGLUTARIC ANHYDRIDE
• ETHYL HEPTAFLUOROBUTYRATE
• Perfluoropropionic acid
• METHYL HEPTAFLUOROBUTYRATE
• Heptafluorobutyric acid
• PERFLUORODECANOIC ACID
• ETHYL PENTAFLUOROPROPIONATE
• Pentadecafluorooctanoic acid
• 2,2,3,3,4,4,4-Heptafluoro-1-butanol
• HEXAFLUOROGLUTARIC ACID
• SILVER PENTAFLUOROPROPIONATE