5-Methyl-2-pyrazinecarboxylic acid Chemical Properties

Melting point:

167-171 °C(lit.)

Boiling point:

253.51°C (rough estimate)

Density 

1.3471 (rough estimate)

refractive index 

1.5100 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Amorphous Powder

pka

3.53±0.10(Predicted)

color 

Orange

BRN 

116005

InChI

InChI=1S/C6H6N2O2/c1-4-2-8-5(3-7-4)6(9)10/h2-3H,1H3,(H,9,10)

InChIKey

RBYJWCRKFLGNDB-UHFFFAOYSA-N

SMILES

C1(C(O)=O)=NC=C(C)N=C1

LogP

-0.254 (est)

CAS DataBase Reference

5521-55-1(CAS DataBase Reference)

NIST Chemistry Reference

2-Methylpyrazine-5-carboxylic acid(5521-55-1)

Safety Information

Hazard Codes 

Xi

Risk Statements 

41-36/37/38

Safety Statements 

26-39-36

WGK Germany 

1

Hazard Note 

Irritant

HS Code 

29339990

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

5-Methyl-2-pyrazinecarboxylic acid Usage And Synthesis

Chemical Properties

Pale Brown Powder

Uses

5-Methyl-2-pyrazinecarboxylic acid may be used in the preparation of novel europium(III) complexes, (5-methyl-2-pyrazinecarboxylato) (phenanthroline)europium(III). It may be used in the synthesis of Ln-metal organic frameworks (MOFs).

General Description

5-Methyl-2-pyrazinecarboxylic acid is a pyrazine derivative. Simultaneous membrane based solvent extraction (MBSE) and membrane based solvent stripping (MBSS) of 5-methyl-2-pyrazine carboxylic acid (MPCA) has been studied. Mechanism of pertraction of MPCA through layered bulk liquid membranes has been studied. MPCA reacts with Ln(NO₃)₃·6H₂O and K₄[W(CN)₈]·2H₂O to form unique three-dimensional network structure which contains open channels.

Synthesis

5-Methylpyrazine-2-carboxylic acid is an intermediate of the lipid-lowering drug amoximus. It can be prepared by electrolytic oxidation of 2,5-dimethyl or 2-methyl-5-(substituted) methylpyrazine.

5-Methyl-2-pyrazinecarboxylic acid(5521-55-1)Related Product Information

• Methyl acrylate
• Glipizide
• Ethyl 2-(Chlorosulfonyl)acetate
• Tetramethylpyrazine
• Kresoxim-methyl
• Pyrazinamide
• 2-Methylpyrazine
• Thiophanate-methyl
• METHYL THIOPHENE-2-CARBOXYLATE
• Sulfachoropyrazine sodium
• Methylparaben
• Bensulfuron methyl
• Methyl
• Parathion-methyl
• Methyl bromide
• 5-Methyl-2,3-pyrazinedicarboxylic acid
• 2-Methyl-5-pyrazinecarboxylic acid methyl ester
• 2,5-PYRAZINEDICARBOXYLIC ACID DIHYDRATE