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H-THR(TBU)-OH

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H-THR(TBU)-OH Basic information

Product Name:
H-THR(TBU)-OH
Synonyms:
  • H-THR(BUT)-OH
  • H-THR(TBU)-OH
  • O-TERT-BUTYL-L-THREONINE
  • O-T-BUTYL-L-THREONINE HYDROCHLORIDE
  • O-T-BUTYL-L-THREONINE
  • THREONINE(TBU)-OH
  • (2S,3R)-2-amino-3-tert-butoxybutanoic acid
  • O-(tert-butyl)-L-threonine(SALTDATA: FREE)
CAS:
4378-13-6
MF:
C8H17NO3
MW:
175.23
EINECS:
610-143-6
Product Categories:
  • Amino Acids
  • Amino Acids and Derivatives
  • Amino Acid Derivatives
  • Peptide Synthesis
  • Threonine
Mol File:
4378-13-6.mol
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H-THR(TBU)-OH Chemical Properties

Melting point:
244-247 °C
Boiling point:
275℃
Density 
1.055
Flash point:
120℃
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka
2.14±0.10(Predicted)
form 
Solid
color 
White to Almost white
optical activity
[α]20/D 43±2°, c = 1% in H2O
BRN 
2206127
Major Application
peptide synthesis
InChI
1S/C8H17NO3/c1-5(6(9)7(10)11)12-8(2,3)4/h5-6H,9H2,1-4H3,(H,10,11)/t5-,6+/m1/s1
InChIKey
NMJINEMBBQVPGY-RITPCOANSA-N
SMILES
C[C@@H](OC(C)(C)C)[C@H](N)C(O)=O
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29241990
Storage Class
11 - Combustible Solids

MSDS

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H-THR(TBU)-OH Usage And Synthesis

Chemical Properties

White powder

Uses

O-tert-Butyl-L-threonine is a catalyst used in direct asymmetric Mannich, Mannich-type, and adol reaction involving unmodified α-hydroxyketones.

reaction suitability

reaction type: solution phase peptide synthesis

H-THR(TBU)-OH Preparation Products And Raw materials

Preparation Products

H-THR(TBU)-OHSupplier

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