2-Amino-4-(trifluoromethyl)pyridine Chemical Properties

Melting point:

70-74 °C

Boiling point:

221.3±40.0 °C(Predicted)

Density 

1.368±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

pka

4.55±0.11(Predicted)

form 

Powder, Solid or Crystalline

color 

White to pale brown

BRN 

7869677

InChI

InChI=1S/C6H5F3N2/c7-6(8,9)4-1-2-11-5(10)3-4/h1-3H,(H2,10,11)

InChIKey

RWGBXAQMUBGGKQ-UHFFFAOYSA-N

SMILES

C1(N)=NC=CC(C(F)(F)F)=C1

CAS DataBase Reference

106447-97-6(CAS DataBase Reference)

Safety Information

Hazard Codes 

T,Xi,C

Risk Statements 

25-36/37/38-43-34-22

Safety Statements 

26-36/37-45-36/37/39

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

3

Hazard Note 

Toxic

HazardClass 

IRRITANT

HazardClass 

6.1

PackingGroup 

II

HS Code 

29333990

MSDS

• Language:English Provider:ALFA

2-Amino-4-(trifluoromethyl)pyridine Usage And Synthesis

Uses

2-Amino-4-trifluoromethylpyridine is a 2-amino-substituted nitrogen-containing six-membered heterocyclic compound, which is used as an important pharmaceutical intermediate.

Synthesis

2-Amino-4-(trifluoromethyl)pyridine can be synthesized by chemical reaction of 2-fluoro-4-trifluoromethyl-pyridine, acetamidine hydrochloride, NaOH, H2O and dimethyl sulfoxide under certain conditions.

References

[1] Patent: US2010/234607, 2010, A1. Location in patent: Page/Page column 4

2-Amino-4-(trifluoromethyl)pyridine(106447-97-6)Related Product Information

• 3-Trifluoromethylpyridine
• 4-Methylpyridin-2-amine
• 4-(Trifluoromethyl)pyridine
• Glycine
• 6-Aminocaproic acid
• 3-Aminopyridine
• 4-Methylpyridine
• 2-Aminopyridine
• 2,4,6-Collidine
• 2-Chloro-4-(trifluoromethyl)pyridine
• Lithium bis(trimethylsilyl)amide
• ALTRENOGEST
• 4-Dimethylaminopyridine
• 2-(Trifluoromethyl)pyridine
• Pyridine
• Tris(hydroxymethyl)aminomethane
• 4-Amino-3-(trifluoromethyl)pyridine
• 2-(1-METHYLHYDRAZINO)-4-(TRIFLUOROMETHYL)PYRIDINE