Pseudohypericin Chemical Properties

Boiling point:

1089.1±65.0 °C(Predicted)

Density 

1.994±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

form 

powder

pka

7.16±0.20(Predicted)

color 

brown

CAS DataBase Reference

55954-61-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22

Safety Statements 

22-36

WGK Germany 

3

Hazardous Substances Data

55954-61-5(Hazardous Substances Data)

Pseudohypericin Usage And Synthesis

Uses

Pseudohypericin is a specific inhibitor of protein kinase C and D-β-Hydroxylase. Also, it is used in determination of potential drug candidate molecules of Hypericum perforatum for COVID-19 treatment.

Definition

ChEBI: Pseudohypericin is an ortho- and peri-fused polycyclic arene.

Enzyme inhibitor

This anti-retroviral agent (FW = 520.45 g/mol) inhibits protein kinase C with an IC50 value of 28.7 μM and dopamine b-hydroxylase with IC50 = 3 μM. Pseudohypericin is a component of St. John’s Wort (Hypericum perforatum). Target(s): dopamine b-hydroxylase; inositoltrisphosphate 3-kinase; and protein kinase C.

Pseudohypericin(55954-61-5)Related Product Information

• Hypericin
• Cresol
• 1,3-DIHYDROXYNAPHTHALENE
• Triphenylene
• 2-HYDROXY-1-NAPHTHALDEHYDE
• Chrysene
• 3-HYDROXY-PHENANTHRENE
• 4-Hydroxy-1-naphthaldehyde
• 1,4-DIMETHYLNAPHTHALENE
• 1-HYDROXY-PHENANTHRENE
• 2'-HYDROXY-1'-ACETONAPHTHONE
• Perylene
• 4-METHYL-2-NAPHTHOL
• 1-METHYLCHRYSENE
• 2-HYDROXY-PHENANTHRENE
• (1-METHYLNAPHTHALEN-4-YL)METHANOL
• 4-METHYL-1-NAPHTHOL
• 4-HYDROXY-PHENANTHRENE