DL-Lactide
DL-Lactide Basic information
- Product Name:
- DL-Lactide
- Synonyms:
-
- 2,5-dimethyl-3,6-dioxo-1,4-dioxane
- 2,5-dioxo-3,6-dimethyl-1,4-dioxane
- 2-hydroxy-propanoicacibimol.cyclicester
- 3,6-diketo-2,5-dimethyl-1,4-dioxane
- 3,6-Dimethyl-2,5-dioxo-1,4-dioxane
- 3,6-dimethyl-p-dioxane-2,5-dione
- 3,6-dimethyl-p-dioxane-5-dione
- D,L-Lactide S
- CAS:
- 95-96-5
- MF:
- C6H8O4
- MW:
- 144.13
- EINECS:
- 202-468-3
- Product Categories:
-
- Biodegradable Polymer Monomers
- Building Blocks
- Carbonyl Compounds
- Chemical Synthesis
- Lactones
- Materials Science
- Dioxanes
- Dioxanes & Dioxolanes
- Functional Materials
- Lactones & Lactides (for High-Performance Polymer Research)
- Reagent for High-Performance Polymer Research
- Monomers
- Organic Building Blocks
- Polymer Science
- 95-96-5
- PLGA
- Mol File:
- 95-96-5.mol
DL-Lactide Chemical Properties
- Melting point:
- 116-119 °C
- Boiling point:
- 142 °C8 mm Hg(lit.)
- Density
- 1.186±0.06 g/cm3(Predicted)
- vapor pressure
- 0.311Pa at 25℃
- Flash point:
- 180°C
- storage temp.
- 2-8°C
- solubility
- Soluble in chloroform and methanol. Slightly soluble in benzene.
- form
- Crystalline Powder
- color
- White
- Water Solubility
- 16.3g/L at 20℃
- Sensitive
- Moisture Sensitive
- BRN
- 82121
- LogP
- 0.4 at 25℃
- NIST Chemistry Reference
- 1,4-Dioxane-2,5-dione, 3,6-dimethyl-(95-96-5)
- EPA Substance Registry System
- 1,4-Dioxane-2,5-dione, 3,6-dimethyl- (95-96-5)
Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-36
- Safety Statements
- 26-37/39
- WGK Germany
- 2
- RTECS
- JH1100000
- TSCA
- Yes
- HS Code
- 29322090
MSDS
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
DL-Lactide Usage And Synthesis
Uses
DL-Lactide is used to produce 2-hydroxy-propionic acid 1-(1-phenyl-ethoxycarbonyl)-ethyl ester. It acts as an important raw material and an intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyes. It is involved in enzymatic alcoholysis to produce both alkyl (R)-lactates and alkyl (S,S)-lactyllactates.DL-Lactide is often used as a protective layer in wound coatings, or as anchors, screws or mesh in surgery, since it degrades in about six months to the innocuous lactic acid.
Chemical Properties
White crystalline powder
Uses
DL-Lactide is used to produce 2-hydroxy-propionic acid 1-(1-phenyl-ethoxycarbonyl)-ethyl ester. It acts as an important raw material and an intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyes. It is involved in enzymatic alcoholysis to produce both alkyl (R)-lactates and alkyl (S,S)-lactyllactates.
Uses
Enzymatic alcoholysis of this racemic lactide catalyzed by commercial Novozym® 435 produces both alkyl (R)-lactates and alkyl (S,S)-lactyllactates in good yield and high enantiopurity.
Definition
ChEBI: Lactide is a member of dioxanes.
General Description
3,6-Dimethyl-1,4-dioxane-2,5-dione (or rac-lactide), is the 50:50 racemic mixture of D- and L-Lactide. Rac-lactide is a lactone derived from lactic acid that has attracted great interest in academia and commercial applications, as it is derived from abundant renewable resources. Rac-lactide can be ready polymerized via ring-opening polymerization, using a variety of metal or organocatalysts, yielding poly(D,L-lactide). While the resulting polymer is generally amorphous, the use of stereospecific catalysts can lead to heterotactic PLA, which exhibits some degree of crystallinity.
Flammability and Explosibility
Non flammable
DL-Lactide Preparation Products And Raw materials
Preparation Products
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