Dihydrostreptomycin sulfate
Dihydrostreptomycin sulfate Basic information
- Product Name:
- Dihydrostreptomycin sulfate
- Synonyms:
-
- D-Streptamine, O-2-deoxy-2-(methylamino)-.alpha.-L-glucopyranosyl-(1?2)-O-5-deoxy-3-C-(hydroxymethyl)-.alpha.-L-lyxofuranosyl-(1?4)-N,N-bis(aminoiminomethyl)-, sulfate (2:3) (salt)
- dihydrostreptomycin solution
- DIHYDROSTREPTOMYCINSULPHATE(INJ.)
- DIHYDROSTREPTOMYCINSULPHATE(ORAL)
- dihydrostreptomycin3/2sulfate
- dihydro-streptomycisulfate(2:3)(salt)
- d-streptamine,o-2-deoxy-2-(methylamino)-alpha-l-glucopyranosyl-(1.fwdarw.2)-o
- n’-bis(aminoiminomethyl)--3-c-(hydroxymethyl)-alpha-l-lyxofuranosyl-(1-4)-
- CAS:
- 5490-27-7
- MF:
- C21H43N7O16S
- MW:
- 681.67
- EINECS:
- 226-823-7
- Product Categories:
-
- Agro-Products
- Amines
- PHARMACEUTICALS
- A - KAntibiotics
- Carbohydrates & Derivatives
- Intermediates & Fine Chemicals
- AminoglycosidesAntibiotics
- Antibiotics A-FAntibiotics
- Antibiotics by Application
- AntimycobacterialAntibiotics
- Chemical Structure Class
- Genetic Marker SelectionAntibiotics
- Interferes with Protein SynthesisMore...Close...
- Mechanism of Action
- Antibacterial
- Antibiotics A to
- Spectrum of Activity
- Mol File:
- 5490-27-7.mol
Dihydrostreptomycin sulfate Chemical Properties
- alpha
- D25 -88.5° (1% soln)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- H2O: 50 mg/mL, clear, faintly yellow
- form
- crystalline
- color
- white to light yellow
- Water Solubility
- Soluble in water
- Merck
- 13,3201
- BRN
- 3894221
- Stability:
- Hygroscopic
- EPA Substance Registry System
- D-Streptamine, O-2-deoxy-2-(methylamino)-.alpha.-L-glucopyranosyl-(1.fwdarw.2)-O-5-deoxy-3-C-(hydroxymethyl)-.alpha.-L-lyxofuranosyl-(1.fwdarw.4)-N,N'-bis(aminoiminomethyl)-, sulfate (2:3) (salt) (5490-27-7)
Dihydrostreptomycin sulfate Usage And Synthesis
Chemical Properties
White Solid
Originator
Dihydrostrepto,MSD ,US,1948
Uses
Dihydrostreptomycin sesquisulfate is used in veterinary medicine to treat bovine infection and also as an effective antibiotic to control pests found in crops.. Other studies have also used it as an electrode for a cochlear amplifier in the hair-cell bundle of lizards.
Uses
As a derivative of Streptomycin (S687500) with antimicrobial activity, Dihydrostreptomycin sulfate is used in veterinary medicine to treat bovine infection and also as an effective antibiotic to control pests found in crops.
Uses
antibacterial, tuberculostatic
Manufacturing Process
Dihydrostreptomycin sulfate may be prepared from streptomycin sulfate by catalytic hydrogenation (Merck, Pfizer, Cyanamid), electrolytic reduction (Schenley, Olin Mathieson), or by sodium borohydride reduction (Bristol), or by isolation from a fermentation process (Takeda).
Therapeutic Function
Antibiotic
Purification Methods
It crystallises from H2O, MeOH, n-BuOH or methyl ethyl ketone. The crystals are not hygroscopic like the amorphous powder; however, both forms are soluble in H2O but the amorphous solid is about 10 times more soluble than the crystals. The free base also crystallises from H2O/Me2CO and has [] D -92o (aqueous solution pH 7.0). [Solomons & Regina Science 109 515 1949, Wolf et al. Science 109 515 1949, McGilveray & Rinehart J Am Chem Soc 87 4003 1956]. [Beilstein 18 III/IV 7538.]
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Dihydrostreptomycin sulfate(5490-27-7)Related Product Information
- Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
- Dihydrostreptomycin
- DIHYDROLIPOIC ACID
- Dipotassium hydrogen phosphate trihydrate
- Vanadyl sulfate
- Sodium sulfate
- Magnesium sulfate heptahydrate
- Barium sulfate
- Zinc sulfate heptahydrate
- Aluminum sulfate
- Hydrochlorothiazide
- Potassium hydrogen phthalate
- Sodium phosphate dibasic dodecahydrate
- Aluminum dihydrogen phosphate
- Ammonium dihydrogen phosphate
- STREPTAVIDIN
- alpha-Dihydroartemisinin
- Stanolone