Basic information Safety Supplier Related

NORCODEINE

Basic information Safety Supplier Related

NORCODEINE Basic information

Product Name:
NORCODEINE
Synonyms:
  • NORCODEINE
  • (5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-3-methoxymorphinan-6-ol
  • 7,8-didehydro-4,5-alpha-epoxy-3-methoxy-morphinan-6-alpha-o
  • 7,8-Didehydro-4,5-alpha-epoxy-3-methoxymorphinan-6-alpha-ol
  • 7,8-didehydro-4,5-epoxy-3-methoxy-,(5-alpha,6-alpha)-morphinan-6-o
  • Morphinan-6alpha-ol, 7,8-didehydro-4,5alpha-epoxy-3-methoxy-
  • Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-, (5alpha,6alpha)-
  • N-Demethylated codeine
CAS:
467-15-2
MF:
C17H19NO3
MW:
285.34
EINECS:
207-388-2
Product Categories:
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
Mol File:
467-15-2.mol
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NORCODEINE Chemical Properties

Melting point:
1850C
Boiling point:
467.7±45.0 °C(Predicted)
Density 
1.37±0.1 g/cm3(Predicted)
Flash point:
9℃
storage temp. 
-20°C
solubility 
DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 10 mg/ml
form 
A crystalline solid
pka
pKa 9.23± 0.01(H2O,t =25±0.1,I=0.15(KCl)Ar)(Approximate)
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Safety Information

Hazard Codes 
F,T
Risk Statements 
11-23/24/25-39/23/24/25
Safety Statements 
7-16-36/37-45
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
1
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NORCODEINE Usage And Synthesis

Chemical Properties

Crystalline Solid

Uses

(-)-N-Norcodeine is a metabolite of Codeine. Morphine derivative.

Definition

ChEBI: A morphinane-like compound that is the N-demethylated derivative of codeine.

Purification Methods

It crystallises from acetone or ethyl acetate. [Speyer & Walther Chem Ber 63 822 1930.] The hydrochloride has m 309o(dec) when crystallised from H2O. [Beilstein 18 III/IV 8091.]

NORCODEINESupplier

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NORCODEINE(467-15-2)Related Product Information