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5-Formylsalicylic acid

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5-Formylsalicylic acid Basic information

Product Name:
5-Formylsalicylic acid
Synonyms:
  • 5-FORMYLSALICYLIC ACID
  • 5-FORMYL-2-HYDROXYBENZOIC ACID
  • 2-HYDROXY-5-FORMYLBENZOIC ACID
  • 5-FORMYLSALICYLIC ACID 97%
  • 5-Formylsalicylic acid purum, >=95.0% (T)
  • 2-hydroxy-5-methanoyl-benzoic acid
  • 3-Carboxy-4-hydroxybenzaldehyde
  • 6-Hydroxyisophthalaldehydic acid
CAS:
616-76-2
MF:
C8H6O4
MW:
166.13
EINECS:
210-492-0
Product Categories:
  • Aldehydes
  • Building Blocks
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
  • C8
  • Chemical Synthesis
  • Organic Building Blocks
  • Intermediates of Dyes and Pigments
  • Acids and Derivatives
  • Carbonyl Compounds
  • Benzene derivatives
  • 616-76-2
Mol File:
616-76-2.mol
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5-Formylsalicylic acid Chemical Properties

Melting point:
250 °C (dec.) (lit.)
Boiling point:
214.32°C (rough estimate)
Density 
1.2208 (rough estimate)
refractive index 
1.4611 (estimate)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
powder
pka
2.67±0.10(Predicted)
color 
brownish-yellow
BRN 
2640881
Stability:
Hygroscopic
CAS DataBase Reference
616-76-2(CAS DataBase Reference)
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Safety Information

Risk Statements 
36/37/38
Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
29189900

MSDS

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5-Formylsalicylic acid Usage And Synthesis

Chemical Properties

light beige fine crystalline powder

Uses

5-Formylsalicylic Acid is used as a selective phase for the extraction of iron(III) in silica gel. It is also used in preparation of styrylquinolines as potent HIV-1 integrase inhibitors that block HIV-1 replication in CEM cells.

Definition

ChEBI: 5-formylsalicylic acid is a monohydroxybenzoic acid in which a benzoic acid nucleus is substituted at positions 2 and 5 by a formyl group and an hydroxy group respectively. It is a member of benzaldehydes, a monohydroxybenzoic acid and a member of phenols. It is functionally related to a salicylic acid.

5-Formylsalicylic acid Preparation Products And Raw materials

Raw materials

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