Basic information Safety Supplier Related

REMOXIPRIDE HYDROCHLORIDE

Basic information Safety Supplier Related

REMOXIPRIDE HYDROCHLORIDE Basic information

Product Name:
REMOXIPRIDE HYDROCHLORIDE
Synonyms:
  • (-)-fla732
  • (s)-(-)-2-((3-bromo-2,6-dimethoxybenzamido)methyl)-1-ethylpyrrolidinehydroch
  • (s)-(-)-3-bromo-2,6-dimethoxy-n-(1-ethyl-2-pyrrolidinylmethyl)benzamidehydro
  • (s)-(-)-d
  • 3-bromo-2,6-dimethoxy-n-(1-ethyl-2-pyrrolidinylmethyl)-benzamidhydrochlori
  • S-(-)-3-BROMO-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2,6-DIMETHOXYBENZAMIDE HCL
  • (S)-(-)-3-BROMO-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]2,6-DIMETHOXYBENZAMIDE HYDROCHLORIDE
  • REMOXIPRIDE HYDROCHLORIDE
CAS:
73220-03-8
MF:
C16H24BrClN2O3
MW:
407.73
Product Categories:
  • Dopamine receptor
  • Aromatics
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
73220-03-8.mol
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REMOXIPRIDE HYDROCHLORIDE Chemical Properties

Melting point:
168-169 °C
storage temp. 
Store at RT
solubility 
Chloroform (Sparingly), Water (Slightly, Sonicated)
form 
White solid.
color 
White to Off-White
Water Solubility 
Soluble to 100 mM in water
Stability:
Hygroscopic
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REMOXIPRIDE HYDROCHLORIDE Usage And Synthesis

Uses

Specific dopamine D2-receptor antagonist. Antipsychotic.

Biological Activity

Standard D 2 receptor antagonist showing some selectivity over D 3 and D 4 receptors (K i values are ~ 300, ~ 1600, and ~ 2800 nM for D 2 , D 3 and D 4 receptors respectively). In vivo remoxipride is an antipsychotic which does not cause extrapyramidal side effects and is 50-fold more potent than sulpiride in antagonising the effects of apomorphine in the rat.

REMOXIPRIDE HYDROCHLORIDESupplier

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