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Ethyl 3-(3,5-dichlorophenyl)-3-oxopropanoate

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Ethyl 3-(3,5-dichlorophenyl)-3-oxopropanoate Basic information

Product Name:
Ethyl 3-(3,5-dichlorophenyl)-3-oxopropanoate
Synonyms:
  • ETHYL (3,5-DICHLOROBENZOYL)ACETATE
  • 3-(3,5-DICHLOROPHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
  • ETHYL 3-(3,5-DICHLOROPHENYL)-3-OXOPROPANOATE
  • Benzenepropanoic acid, 3,5-dichloro-b-oxo-, ethyl ester
  • 3-(3,5-Dichlorophenyl)-3-oxo-propionic acid ethyl este
  • Ethyl 3,5-dichloro-β-oxobenzenepropanoate
  • Benzenepropanoic acid, 3,5-dichloro-β-oxo-, ethyl ester
CAS:
172168-01-3
MF:
C11H10Cl2O3
MW:
261.1
Mol File:
172168-01-3.mol
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Ethyl 3-(3,5-dichlorophenyl)-3-oxopropanoate Chemical Properties

Boiling point:
353.9±37.0 °C(Predicted)
Density 
1.319±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
9.98±0.50(Predicted)
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Ethyl 3-(3,5-dichlorophenyl)-3-oxopropanoate Usage And Synthesis

Synthesis

Ethyl 3,5-dichlorobenzoate (5 g, 22.8 mmol) and sodium hydride (1.10 g, 27.4 mmol) were dissolved in 35 mL THF under N2. Then 7.8 mL ethyl acetate was added slowly at room temperature and refluxed overnight. The solvent was removed under reduced pressure. The residue was extracted with ethyl acetate, washed with water and brine, and dried over Na2SO4 to afford Ethyl 3-(3,5-dichlorophenyl)-3-oxopropanoate.

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