Dipotassium glycyrrhizinate Chemical Properties

Melting point:

>215oC (dec.)

Density 

1.277 at 20℃

vapor pressure 

0Pa at 20℃

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly)

form 

Solid

color 

White to Off-White

Stability:

Hygroscopic

InChI

InChI=1/C42H62O16.K.H/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50;;/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54);;/t19-,21-,22-,23-,24-,25-,26-,27+,28-,29-,30+,31+,34-,35-,38+,39-,40-,41+,42+;;/s3

InChIKey

BIVBRWYINDPWKA-VLQRKCJKSA-L

SMILES

C[C@@]12CC[C@@]3([H])C([C@@H](O[C@@]4([H])O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]4O[C@@]4([H])[C@@H]([C@@H](O)[C@H](O)[C@@H](C(=O)O)O4)O)CC[C@]3(C)[C@@]1([H])C(C=C1[C@]3([H])C[C@@](C)(C(=O)O)CC[C@]3(C)CC[C@@]21C)=O)(C)C.[KH] |&1:1,4,7,9,12,16,18,20,22,24,25,27,29,37,39,44,47,54,58,r|

Surface tension

55.4mN/m at 880mg/L and 20℃

CAS DataBase Reference

68797-35-3(CAS DataBase Reference)

EPA Substance Registry System

.alpha.-D-Glucopyranosiduronic acid, (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-.beta.-D-glucopyranuronosyl-, dipotassium salt (68797-35-3)

Safety Information

HS Code 

2938.90.0000

Dipotassium glycyrrhizinate Usage And Synthesis

Chemical Properties

Dipotassium glycyrrhizinate (DPG), an active ingredient derived from the root of the leguminous plant licorice (Glycyrrhizauralensis Fisch.), is an off-white to light yellow powder that is odorless and has a distinct sweet taste that lasts for a long time. It is approximately 150 times sweeter than sucrose and is easily soluble in water, dilute ethanol, glycerin, and propylene glycol. It is slightly soluble in absolute ethanol and ether. DPG finds extensive utilization in medicine, food, beverage, and healthcare products.

Uses

Dipotassium Glycyrrhizinate is used in improving the dissolution property of amphotericin B (AMB) and the bioavailability of the drug incorporated in suppositories.

Definition

ChEBI: Glycyrrhizinate dipotassium is an organic molecular entity.

benefits

Dipotassium glycyrrhizinate is a liquorice derivative that helps reduce skin redness and inflammation, thanks to its anti-irritant, calming, and soothing properties. Its sebum-regulating properties inhibit the excessive production of skin lipids by the sebaceous glands. It can be incorporated successfully into sensitive skin products, while also appearing to help improve oily skin. Dipotassium Glycyrrhizinate is suitable not only for hair and skin care but also for oral hygiene.

References

https://www.alexmo-cosmetics.de/Dipotassium-Glycyrrhizinate_1
https://www.paulaschoice.com/ingredient-dictionary/ingredient-dipotassium-glycyrrhizate.html
Effects of dipotassium glycyrrhizinate on wound healing doi: 10.1590/ACB360801
A re-analysis of studies regarding the use of Glycyrrhiza spp. in women during pregnancy doi:10.1016/j.hermed.2014.01.005

Dipotassium glycyrrhizinate(68797-35-3)Related Product Information

• Diammonium glycyrrhizinate
• DISODIUM GLYCYRRHIZATE
• 18β-Glycyrrhetinic Acid
• 11-Deoxo-18beta-glycyrrhetic acid
• trans-4-Propylcyclohexanecarboxylic acid
• Monopotassium glycyrrhizate
• trans-4-Hexylcyclohexanecarboxylic acid
• N-OCTYL ALPHA-D-GLUCOPYRANOSIDE
• Potassium L-lactate
• trans-4-Butylcyclohexanecarboxylic acid
• Glycyrrhizic acid
• Isophorone
• trans-4-Pentylcyclohexanecarboxylic acid
• SOPHOROSE
• Dipotassium glycyrrhizinate
• Potassium
• 7-NONADECENOIC ACID
• D-PIPERITONE