ChemicalBook > Product Catalog > Organic Chemistry > Alcohols,Phenols,Phenol alcohols > Phenol Alcohols derivatives > (-)-Nephthenol
(-)-Nephthenol
(-)-Nephthenol Basic information
- Product Name:
- (-)-Nephthenol
- Synonyms:
-
- (-)-Nephthenol
- (R,3E,7E,11E)-α,α,4,8,12-Pentamethylcyclotetradeca-3,7,11-triene-1-methanol
- 2-[(1R,4E,8E,12E)-4,8,12-Trimethyl-4,8,12-cyclotetradecatriene-1-yl]-2-propanol
- Nephthenol
- (R)-nephthenol
- 3,7,11-Cyclotetradecatriene-1-methanol, α,α,4,8,12-pentamethyl-, (1R,3E,7E,11E)-
- CAS:
- 53915-41-6
- MF:
- C20H34O
- MW:
- 290.48
- Mol File:
- 53915-41-6.mol
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(-)-Nephthenol Chemical Properties
- Boiling point:
- 394.6±42.0 °C(Predicted)
- Density
- 0.881±0.06 g/cm3(Predicted)
- pka
- 15.03±0.29(Predicted)
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(-)-Nephthenol Usage And Synthesis
Uses
Nephthenol is a terpenoid that can be isolated from Nephthea brassica. Nephthenol exhibits cytotoxicity in cells A549, HT-29, KB and P-388 with IC50s of 2.72, 3.01, 1.84, and 0.42 μg/mL, respectively[1].
Definition
ChEBI: A cembrane diterpenoid obtained by regio- and stereoselective hydration of the exocyclic double bond of cembrene C.
References
[1] Duh CY, et al., Cytotoxic terpenoids from the Formosan soft coral Nephthea brassica. J Nat Prod. 1999 Nov;62(11):1518-21. DOI:10.1021/np990212d
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