(6-Chloro-3-indolyl)-β-D-glucuronide cyclohexylammonium salt Chemical Properties

storage temp. 

2-8°C

solubility 

DMSO: 10 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.50 mg/ml

form 

A crystalline solid

optical activity

[α]20/D 70.5±2°, c = 1% in DMF/H2O 1:1

Sensitive 

Moisture Sensitive

CAS DataBase Reference

138182-20-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-24/25

WGK Germany 

3

F 

10

HS Code 

29389090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

(6-Chloro-3-indolyl)-β-D-glucuronide cyclohexylammonium salt Usage And Synthesis

Description

6-Chloro-3-indolyl-β-D-glucuronide is a chromogenic substrate for β-glucuronidase. Upon cleavage by β-glucuronidase, an insoluble salmon precipitate is formed that can be used in histochemical analysis of β-glucuronidase activity.

Chemical Properties

solid

Uses

6-Chloro-3-indolyl-β-D-glucuronide Cyclohexylammonium Salt is a chromogenic substrate for β-glucuronidase yielding a salmon colored precipitate upon cleavage. It can also be used as reactant/reagent in biological study of hydrolysis of glucuronide-based substrates mediated by tungsten, Cu2+, Fe2+, and Zn2+.

Uses

(6-Chloro-3-indolyl)-β-D-glucuronide cyclohexylammonium salt is used for the detection of β-Glucuronidase and is an alternative to X-Glucuronide.

References

[1] C. WOZNIAK L O. Hydrolysis of glucuronide‐based substrates mediated by tungsten, Cu2+, Fe2+, and Zn2+[J]. Physiologia plantarum, 1996, 166 1: 484-490. DOI: 10.1111/j.1399-3054.1996.tb00462.x

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