Basic information Safety Supplier Related

GLY-PHE BETA-NAPHTHYLAMIDE

Basic information Safety Supplier Related

GLY-PHE BETA-NAPHTHYLAMIDE Basic information

Product Name:
GLY-PHE BETA-NAPHTHYLAMIDE
Synonyms:
  • glycylphenylalanine2-naphthylamide
  • GLY-PHE BETA-NAPHTHYLAMIDE
  • H-GLY-PHE-BETA-NA
  • gly-phe B-naphthylamide
  • gly-phe β-naphthylamide
  • H-Gly-Phe-bNA
  • glycyl-L-phenylalanine 2-naphthylamide
  • (S)-N-(2-(2-Aminoacetamido)-3-phenylpropanoyl)-2-naphthamide
CAS:
21438-66-4
MF:
C21H21N3O2
MW:
347.41
Product Categories:
  • Cathepsin CCathepsin
  • Cathepsin CCathepsin/Granzyme Inhibitors&Substrates
  • Enzyme Substrates
  • Fluorimetric
  • Substrates
  • Substrates by Enzyme
Mol File:
21438-66-4.mol
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GLY-PHE BETA-NAPHTHYLAMIDE Chemical Properties

Boiling point:
692.4±55.0 °C(Predicted)
Density 
1.254±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Soluble in 100mg in 200µl DMSO.
form 
crystalline
pka
13.62±0.46(Predicted)
color 
White to off-white
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Safety Information

Hazard Codes 
Xn
Risk Statements 
40
Safety Statements 
22-36
WGK Germany 
3

MSDS

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GLY-PHE BETA-NAPHTHYLAMIDE Usage And Synthesis

Uses

Gly-Phe beta-naphthylamide is used to accumulate inside lysosomes leading to their destruction. Studies report that Gly-Phe-β-naphthylamide significantly inhibits the activation of caspase-8, and has also been used to study recombinant cathepsin C.

Definition

ChEBI: An N-(2-naphthyl)carboxamide obtained by formal condensation of the carboxy group of glycyl-L-phenylalanine with the amino group of 2-naphthylamine.

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