GLY-PHE BETA-NAPHTHYLAMIDE CAS#: 21438-66-4

GLY-PHE BETA-NAPHTHYLAMIDE Basic information

Product Name:

GLY-PHE BETA-NAPHTHYLAMIDE

Synonyms:

glycylphenylalanine2-naphthylamide
GLY-PHE BETA-NAPHTHYLAMIDE
H-GLY-PHE-BETA-NA
gly-phe B-naphthylamide
gly-phe β-naphthylamide
H-Gly-Phe-bNA
glycyl-L-phenylalanine 2-naphthylamide
(S)-N-(2-(2-Aminoacetamido)-3-phenylpropanoyl)-2-naphthamide

CAS:

21438-66-4

MF:

C21H21N3O2

MW:

347.41

Product Categories:

Cathepsin CCathepsin
Cathepsin CCathepsin/Granzyme Inhibitors&Substrates
Enzyme Substrates
Fluorimetric
Substrates
Substrates by Enzyme

Mol File:

21438-66-4.mol

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GLY-PHE BETA-NAPHTHYLAMIDE Chemical Properties

Boiling point:: 692.4±55.0 °C(Predicted)
Density: 1.254±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: Soluble in 100mg in 200µl DMSO.
form: crystalline
pka: 13.62±0.46(Predicted)

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Safety Information

Hazard Codes: Xn
Risk Statements: 40
Safety Statements: 22-36
WGK Germany: 3

MSDS

Language:English Provider:SigmaAldrich

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GLY-PHE BETA-NAPHTHYLAMIDE Usage And Synthesis

Uses

Gly-Phe beta-naphthylamide is used to accumulate inside lysosomes leading to their destruction. Studies report that Gly-Phe-β-naphthylamide significantly inhibits the activation of caspase-8, and has also been used to study recombinant cathepsin C.

Definition

ChEBI: An N-(2-naphthyl)carboxamide obtained by formal condensation of the carboxy group of glycyl-L-phenylalanine with the amino group of 2-naphthylamine.

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