2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONE Chemical Properties

Melting point:

197-200°C

Boiling point:

382.7±45.0 °C(Predicted)

Density 

1.510±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,2-8°C

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

7.65±0.20(Predicted)

color 

Pale Beige to Brown

2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONE Usage And Synthesis

Chemical Properties

Brown Solid

Uses

2-Hydroxyisoquinoline-1,3(2H,4H)-dione was recently discovered as a scaffold for the inhibition of HIV-1 integrase and the RNase H function of HIV-1 reverse transcriptase. Its interaction with Mg2+ and Mn2+ was investigated using different spectroscopic techniques and it was reported that 2-hydroxyisoquinoline-1,3(2H,4H)-dione forms a 1:1 complex with Mg2+ but a 1:2 complex with Mn2+. Antiviral agent.

2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONE(6890-08-0)Related Product Information

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