1-(CHLOROACETYL)-L-PROLINE METHYL ESTER Chemical Properties

Boiling point:

316.2±37.0 °C(Predicted)

Density 

1.285±0.06 g/cm3(Predicted)

pka

-3.02±0.40(Predicted)

1-(CHLOROACETYL)-L-PROLINE METHYL ESTER Usage And Synthesis

Uses

N-Chloroacetyl-L-proline Methyl Ester is an impurity of Vildagliptin (V305000), a class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. Aside from their use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.

1-(CHLOROACETYL)-L-PROLINE METHYL ESTER(38074-72-5)Related Product Information

• vildagliptin Impurity L
• vildagliptin Impurity R
• (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
• (S)-Pyrrolidine-2-carbonitrile hydrochloride
• vildagliptin Impurity Q
• Vildagliptin Related Compound F
• Vildagliptin Related Compound H
• vildagliptin Impurity O
• Vildagliptin Related Compound E
• (S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxaMide
• CHLOROAC-PRO-OH
• Vildagliptin Impurity 10
• Vildagliptin Related Compound G
• VILDAGLIPTIN
• N-acetic acid-1-aMino-3-adaMantanol
• Vildagliptin IMpurity 2 (Mixture of DiastereoMers)
• Vildagliptin Impurity 6
• Vildagliptin N-Oxide