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1-(CHLOROACETYL)-L-PROLINE METHYL ESTER

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1-(CHLOROACETYL)-L-PROLINE METHYL ESTER Basic information

Product Name:
1-(CHLOROACETYL)-L-PROLINE METHYL ESTER
Synonyms:
  • 1-(CHLOROACETYL)-L-PROLINE METHYL ESTER
  • Vildagliptin Impurity 13
  • Vildagliptin Impurity 10/Methyl (2S)-1-(2-chloroacetyl)pyrrolidine-2-carboxylate
  • chloroacetyl L-proline methyl ester
  • vildagliptin Impurity U
  • Vildagliptin Impurity 78
  • L-Proline, 1-(2-chloroacetyl)-, methyl ester
  • (S)-methyl 1-(2-chloroacetyl)pyrrolidine-2-carboxylate
CAS:
38074-72-5
MF:
C8H12ClNO3
MW:
205.64
Mol File:
38074-72-5.mol
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1-(CHLOROACETYL)-L-PROLINE METHYL ESTER Chemical Properties

Boiling point:
316.2±37.0 °C(Predicted)
Density 
1.285±0.06 g/cm3(Predicted)
pka
-3.02±0.40(Predicted)
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1-(CHLOROACETYL)-L-PROLINE METHYL ESTER Usage And Synthesis

Uses

N-Chloroacetyl-L-proline Methyl Ester is an impurity of Vildagliptin (V305000), a class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. Aside from their use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.

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1-(CHLOROACETYL)-L-PROLINE METHYL ESTER(38074-72-5)Related Product Information