Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Heterocyclic compound >  Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate

Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate

Basic information Safety Supplier Related

Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate Basic information

Product Name:
Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate
Synonyms:
  • 1-BOC-4-(6-NITROPYRIDIN-3-YL)PIPERAZINE
  • tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate
  • 4-(6-Nitro-3-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester
  • 4-(6-Nitropyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester
  • NaMe:4-(6-Nitro-3-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester
  • Tert. butyl-4-(6-Nitropyridin-3-yl)piperazino-1-carboxylate
  • 1-Piperazinecarboxylic acid, 4-(6-nitro-3-pyridinyl)-, 1,1-diMethylethyl ester
  • 4-(6-nitro-3-pyridinyl)-1-piperazinecarboxylic acid,1,1-dimethylethyl ester
CAS:
571189-16-7
MF:
C14H20N4O4
MW:
308.33
EINECS:
801-163-8
Product Categories:
  • Anticancer
Mol File:
571189-16-7.mol
More
Less

Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate Chemical Properties

Boiling point:
480.1±45.0 °C(Predicted)
Density 
1.258
storage temp. 
Inert atmosphere,Room Temperature
pka
0.11±0.70(Predicted)
InChI
InChI=1S/C14H20N4O4/c1-14(2,3)22-13(19)17-8-6-16(7-9-17)11-4-5-12(15-10-11)18(20)21/h4-5,10H,6-9H2,1-3H3
InChIKey
SUWKOEMQNOBJEQ-UHFFFAOYSA-N
SMILES
N1(C(OC(C)(C)C)=O)CCN(C2=CC=C([N+]([O-])=O)N=C2)CC1
More
Less

Safety Information

HS Code 
2933599590
More
Less

Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate Usage And Synthesis

Description

Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate is a pharmaceutical intermediate compound that can be used to synthesize the anticancer drug Palbociclib. Palbociclib is used to treat estrogen receptor-positive (ER+) and human epidermal growth factor receptor-negative (HER2-) breast cancer.

Uses

tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate is used in preparation of Heterocyclic compound as cdk-hdac double-channel inhibitor.

Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylateSupplier

TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.
Tel
022-60182192,1339732154 18722583064
Email
marketing@pharmacn.com
Shanghai Boyle Chemical Co., Ltd.
Tel
Email
sales@boylechem.com
Alfa Aesar
Tel
400-6106006
Email
saleschina@alfa-asia.com
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Email
sales.bj@hwrkchemical.com
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18934348241
Email
sales4.gd@hwrkchemical.com
More
Less

Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate(571189-16-7)Related Product Information