1-O-HEXADECYL-SN-GLYCEROL
1-O-HEXADECYL-SN-GLYCEROL Basic information
- Product Name:
- 1-O-HEXADECYL-SN-GLYCEROL
- Synonyms:
-
- CHIMYL ALCOHOL
- 1,2-Propanediol, 3-(hexadecyloxy)-, (2S)-
- α-hexadecylglyceryl ether
- 1-hexadecylglycerol
- 1-o-hexadecylglycerol
- 3-(hexadecyloxy)-2-propanediol
- 1-O-PALMITOYL-SN-GLYCEROL
- 1-O-HEXADECYL-SN-GLYCEROL
- CAS:
- 506-03-6
- MF:
- C19H40O3
- MW:
- 316.52
- EINECS:
- 208-026-6
- Mol File:
- 506-03-6.mol
1-O-HEXADECYL-SN-GLYCEROL Chemical Properties
- Melting point:
- 64°
- alpha
- D20 +3.0° (c = 1.16 in chloroform)
- Boiling point:
- bp0.005 120°
- Density
- 1.0054 (rough estimate)
- refractive index
- 1.4410 (estimate)
- storage temp.
- -15°C
- solubility
- DMF: 16 mg/ml; DMSO: 0.16 mg/ml; Ethanol: 5 mg/ml
- form
- A crystalline solid
- pka
- 13.68±0.20(Predicted)
- LogP
- 6.702 (est)
1-O-HEXADECYL-SN-GLYCEROL Usage And Synthesis
Description
1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether. It reduces UVB-induced cell death and production of reactive oxygen species (ROS) and prostaglandin E2 (PGE2; ) in normal human epidermal keratinocytes (NHEKs). 1-O-Hexadecyl-sn-glycerol (50 μM) increases coronary flow and left ventricular developed pressure and reduces malondialdehyde (MDA) formation ex vivo in a rat heart model of ischemia/reperfusion injury.
Uses
1-O-Hexadecyl-sn-glycerol restores plasmalogen levels in Chinese hamster ovary (CHO) cells and human pulmonary arterial endothelial cells (PAEC). Plasmalogen may play a role in protecting animal cells against photosensitized killing.
Definition
ChEBI: A 1-n-hexadecyl analogue of an optically active alkylglycerol compound.
Purification Methods
Recrystallise it from hexane. [Beilstein 1 III 2322.]
1-O-HEXADECYL-SN-GLYCEROLSupplier
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1-O-HEXADECYL-SN-GLYCEROL(506-03-6)Related Product Information
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- TOMATINE
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- Batyl alcohol
- Ascorbyl Palmitate
- L-BETA,GAMMA-DIHEXADECYL-ALPHA-CEPHALIN
- 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
- SOLASONINE
- TRIARACHIDIN
- Glycerol tristearate
- 1-HEXADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
- 1,2-Distearoyl-sn-glycero-3-phosphocholine
- 1,3-DIPALMITIN
- Madecassoside
- G-STROPHANTHIN