Platinum, dichloro(1,2-cyclohexanediamine-N,N')-, [sp-4-2-(1R-trans)]- Chemical Properties

Melting point:

>256°C (dec.)

storage temp. 

2-8°C

solubility 

DMSO (Slightly)

form 

Solid

color 

Yellow

Major Application

pharmaceutical (small molecule)

InChI

InChI=1/C6H12N2.2ClH.Pt/c7-5-3-1-2-4-6(5)8;;;/h5-8H,1-4H2;2*1H;/q-2;;;+4/p-2/t5-,6-;;;/s3

InChIKey

UUERTZXRKZEANK-SIGUBHPQNA-L

SMILES

[Cl-][Pt+2]1(N[C@]2([H])CCCC[C@@]2([H])N1)[Cl-] |&1:3,9,r|

Safety Information

RIDADR 

UN 3467 6.1 / PGIII

WGK Germany 

WGK 3

HS Code 

2843900000

Storage Class

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications

Carc. 2
Eye Irrit. 2
Muta. 1B
Repr. 1B
STOT RE 1

Platinum, dichloro(1,2-cyclohexanediamine-N,N')-, [sp-4-2-(1R-trans)]- Usage And Synthesis

Uses

[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N’) dichloridoplatinum(II) is an impurity of Oxiplatin (O845075), third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic.