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FUCHSIN BASIC

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FUCHSIN BASIC Basic information

Product Name:
FUCHSIN BASIC
Synonyms:
  • P-ROSANILINE HYDROCHLORIDE
  • RASANILINE HYDROCHLORIDE
  • ROSANILINE
  • ROSANILINE CHLORIDE
  • ROSANILINE HCL
  • AFB STAIN
  • FUCHSIN RAL22 COLD AFB STAIN
  • FUCHSIN SOLUTION, DECOLORIZED R
CAS:
632-99-5
MF:
C20H20ClN3
MW:
337.85
EINECS:
211-189-6
Product Categories:
  • Triphenylmethane
  • Dyes and Pigments
Mol File:
632-99-5.mol
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FUCHSIN BASIC Chemical Properties

Melting point:
250 °C
Boiling point:
300℃[at 101 325 Pa]
Density 
0.999 g/mL at 20 °C
vapor pressure 
0Pa at 25℃
refractive index 
n20/D 1.334
Flash point:
48 °F
storage temp. 
2-8°C
solubility 
H2O: soluble1mg/mL
form 
liquid
Colour Index 
42510
color 
Green to dark green
PH
5-6 (1g/l, H2O, 25°C)
Water Solubility 
4 G/L (25 ºC)
λmax
543 nm
Merck 
14,5652
BRN 
4166684
Biological Applications
Detecting cancer; treating Jock itch,oral fungal infection,piles; periodontal disease
LogP
1.632 at 25℃
IARC
2B (Vol. Sup 7, 57, 99, 100F) 2012
EPA Substance Registry System
C.I. Basic Violet 14 (632-99-5)
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Safety Information

Hazard Codes 
F,Xn
Risk Statements 
40-22
Safety Statements 
7-16-36/37
WGK Germany 
3
RTECS 
CX9850000
TSCA 
Yes
HS Code 
3204 13 00
Hazardous Substances Data
632-99-5(Hazardous Substances Data)

MSDS

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FUCHSIN BASIC Usage And Synthesis

Chemical Properties

Green crystal powder

Uses

As a dye or in manufacture of other dyes.

Uses

Biological stain for distinguishing coli and aerogene bacteriaBasic Fuchsin is useful for Ziehl-Neelson staining to detect acid-fast bacilli. It is also used to stain tubercle bacillus and bacterial flagella. It plays an important role for tissue sections to visualize elastic fibers, cardiac and skeletal muscle tissue. It also acts as bacterial and histological stains. Further, it is used to stain cellular elements, certain tissues, bacteria and also acts as a local anti-infective.

Definition

ChEBI: A hydrochloride that is the monohydrochloride of 4-[(4-aminophenyl)(4-iminocyclohexa-2,5-dien-1-ylidene)methyl]-2-methylaniline. One of the major constituents of Basic fuchsin, together with pararosanilin, magenta II and new fuchsin.

General Description

Dark green powder. A dye derived from triphenylmethane.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

FUCHSIN BASIC neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides. Easily reduced to colorless leuco-bases .

Fire Hazard

Flash point data for FUCHSIN BASIC are not available, but FUCHSIN BASIC is probably combustible.

Flammability and Explosibility

Not classified

Clinical Use

Basic fuchsin is a mixture of the chlorides of rosaniline andp-rosaniline. It exists as a green crystalline powder with ametallic appearance. The compound is soluble in water andin alcohol but insoluble in ether. Basic fuchsin is a componentof carbol–fuchsin solution (Castellani’s paint), which isused topically in the treatment of fungal infections, notablyringworm and athlete’s foot.

Properties and Applications

TEST ITEMS

SPECIFICATION

APPEARANCE

VIOLET

LIGHTING

4-5

SOAPING

4-5

PERSPIRATING

4-5

FRICTION(DRY)

4-5

FRICTION(WET)

4

RESIDUE ON 80 MESH

5.0% max

WATER SOLUBLE

1.0% max

VOLATITE 105 °C

1.0% max

TINTING STRENGTH

100-105 %

WEIGHT METAL TOTAL

50ppm max

Purification Methods

Purify the dye by dissolving it in EtOH, filtering and adding H2O. Filter or centrifuge it and wash the precipitate with Et2O and dry it in air. It has also been recrystallised from water and dried in vacuo at 40o. The crystals have a metallic green lustre. It has UV max in EtOH at 543nm ( 93,000). Its solubility in H2O is 0.26%. A carmine red colour is obtained in EtOH. It is paraRosaniline with a methyl group. [Scalan J Am Chem Soc 57 887 1937.]

FUCHSIN BASIC Preparation Products And Raw materials

Raw materials

FUCHSIN BASICSupplier

J & K SCIENTIFIC LTD.
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Alfa Aesar
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Energy Chemical
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