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Δ2-Cefuroxime Axetil

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Δ2-Cefuroxime Axetil Basic information

Product Name:
Δ2-Cefuroxime Axetil
Synonyms:
  • Δ2-Cefuroxime Axetil
  • (6R,7R)-3-[[(AMinocarbonyl)oxy]Methyl]-7-[[(2Z)-2-(2-furanyl)-2-(MethoxyiMino)acetyl]aMino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic Acid 1-(Acetyloxy)ethyl Ester
  • [6R-[6α, 7β(Z)]]-3-[[(Aminocarbonyl)oxy]methyl]-7-[[2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid 1-(acetyloxy)ethyl ester
  • Cefuroxime Axetil EP Impurity A
  • Cefuroxime Axetil Impurity A (EP)
  • Cefuroxime Axetil Impurities (EP)
  • Cefuroxime Impurity 34(Cefuroxime Axetil EP Impurity A)
  • (6R,7R)-1-acetoxyethyl 3-((carbamoyloxy)methyl)
CAS:
123458-61-7
MF:
C20H22N4O10S
MW:
510.47
Product Categories:
  • Chiral Reagents, Drug Analogues, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
  • Chiral Reagents
  • Drug Analogues
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
Mol File:
123458-61-7.mol
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Δ2-Cefuroxime Axetil Chemical Properties

Melting point:
64-71°C
Density 
1.61±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
8.33±0.60(Predicted)
color 
White to Pale Yellow
Stability:
Hygroscopic
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Δ2-Cefuroxime Axetil Usage And Synthesis

Uses

It is an oral prodrug of Cefuroxime (C248060), an injectable second generation cephalosporin with an excellent antibacterial activity. This ester is applied in therapy as a mixture of the R and S diastereoisomers.

Uses

Δ2-Cefuroxime Axetil (Cefuroxime Axetil EP Impurity A) is an oral prodrug of Cefuroxime (C248060), an injectable second generation cephalosporin with an excellent antibacterial activity. This ester is applied in therapy as a mixture of the R and S diastereoisomers.

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