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Kaerophyllin

Basic information Safety Supplier Related

Kaerophyllin Basic information

Product Name:
Kaerophyllin
Synonyms:
  • Kaerophyllin
  • (-)-Kaerophylin
  • Chaerophyllin
  • 2(3H)-Furanone, 4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4-dimethoxyphenyl)methylene]dihydro-, (3E,4R)-
CAS:
75590-33-9
MF:
C21H20O6
MW:
368.38
Mol File:
75590-33-9.mol
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Kaerophyllin Chemical Properties

solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
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Kaerophyllin Usage And Synthesis

Description

Kaerophyllin can protect the rat liver from TAA-caused injury and fibrogenesis by suppressing hepatic inflammation and inhibiting HSC activation, possibly through upregulation of PPAR-γ expression. Kaerophyllin inhibits AB-induced LX-2 activation and migration with downregulation of Akt/ERK phosphorylations and NF-κB activity.

target

TNF-α | PPAR | Akt | ERK | NF-kB | IL Receptor

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