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7-DeMethyl Ivabradine

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7-DeMethyl Ivabradine Basic information

Product Name:
7-DeMethyl Ivabradine
Synonyms:
  • 3-[3-[[[(7S)-3,4-DiMethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]Methyl]MethylaMino]propyl]-1,3,4,5-tetrahydro-7-hydroxy-8-Methoxy-H-3-benzazepin-2-one
  • 7-O-Desmethyl Ivabradine
  • Ivabradine Impurity j
  • 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7-hydroxy-8-methoxy-2H-3-benzazepin-2-one
  • Ivabradine Impurity D (7-Demethyl Ivabradine)
  • Ivabradine 7-O-Desmethyl Impurity
  • 3-[3-[[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-8-hydroxy-7-methoxy-2,5-dihydro-1H-3-benzazepin-4-one
  • 2H-3-Benzazepin-2-one, 3-[3-[[[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7-hydroxy-8-methoxy-
CAS:
304462-60-0
MF:
C26H34N2O5
MW:
454.56
Product Categories:
  • Amines, Chiral Reagents, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • Amines
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
Mol File:
304462-60-0.mol
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7-DeMethyl Ivabradine Chemical Properties

Melting point:
>50°C (dec.)
Boiling point:
643.9±55.0 °C(Predicted)
Density 
1.186±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Methanol (Slightly)
pka
9.95±0.20(Predicted)
form 
Solid
color 
Off-White to Pale Beige
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7-DeMethyl Ivabradine Usage And Synthesis

Uses

Ivabradine (I940500) metabolite.

Uses

7-Demethyl Ivabradine is an impurity of Ivabradine (I940500), which is a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal.

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