MPEG6-Mal Chemical Properties

storage temp. 

Storage temp. 2-8°C

solubility 

Soluble in DMSO, DCM, DMF

form 

Solid

color 

White to off-white

MPEG6-Mal Usage And Synthesis

Description

m-PEG6-Mal is a PEG linker containing a maleimide group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

m-PEG6-amino-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

MPEG6-Mal(1644231-07-1)Related Product Information

• alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol)
• Mal-PEG4-NHS ester
• MAl-PEG6-t-butyl ester
• 2,5-Dioxopyrrolidin-1-yl 3-methoxypropanoate
• 3,6,9,12,15,18-Hexaoxanonadecane-1-thiol
• Mal-PEG3-alcohol
• 3,6,9,12,15,18,21,24,27-Nonaoxaoctacosanoic acid
• Pentaethylene glycol mono methyl ether tosylate
• MPEG5-NHS
• m-PEG4-Mal
• Mal-PEG3-Mal
• mPEG16-Mal
• MPEG8-NH-Mal
• MPEG3-N3
• MPEG12-Mal
• 13-Azido-2,5,8,11-tetraoxa-tridecane