5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione
5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione Basic information
- Product Name:
- 5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione
- Synonyms:
-
- 5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione
- Elagolix Impurity 19
- 5-bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-4-hydroxy-6-methylpyrimidin-2(1H)-one
- 1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-bromo-6-methyl-2,4(1H,3H)-pyrimidinedione
- 1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-5-bromo-6-methyl-2,4(1H,3H)-pyrimidinedione
- 1-(2-Fluoro-6-(trifluoromethyl)benzyl)-5-bromo-6-methylpyrimidine-2,4(1H,3H)-dione
- 2,4(1H,3H)-Pyrimidinedione, 5-bromo-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-
- 5-Bromo-1-[2-Fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione
- CAS:
- 830346-48-0
- MF:
- C13H9BrF4N2O2
- MW:
- 381.12
- Mol File:
- 830346-48-0.mol
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5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione Chemical Properties
- Melting point:
- >230°C (dec.)
- Density
- 1.684±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
- pka
- 7.83±0.40(Predicted)
- form
- Solid
- color
- White to Off-White
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5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione Usage And Synthesis
Uses
5-Bromo-1-[2-Fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione is an intermediate in the synthesis of Elagolix, a gonadotropin-releasing hormone antagonist (GnRH) used in the treatment of endometriosis.
5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dioneSupplier
Hangzhou Cheminspire Technology Co., Ltd. Gold
- Tel
- 0571-89081561; 10006559855
- info@cheminspire.com
Xiamen Halosyntech Co., Ltd Gold
- Tel
- 0592-6688068 18106901346
- qbl2015@halolife.cn
Shandong RuiYue Biotechnology Co., Ltd. Gold
- Tel
- 0531-88581623 18805314509
- 1456922171@126.com
ChengDu TongChuangYuan Pharmaceutical Co.Ltd
- Tel
- 28-83379370 13880556291
- tcy@tcypharm.com
Adamas Reagent, Ltd.
- Tel
- 400-6009262 16621234537
- chenyj@titansci.com
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5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione(830346-48-0)Related Product Information
- O-Demethyl elagolix sodium
- 2,4(1H,3H)-Pyrimidinedione, 3-[(2R)-2-amino-2-phenylethyl]-5-(2-fluoro-3-hydroxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-
- Carbamic acid, N-[(1R)-2-[5-(2-fluoro-3-hydroxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-1-phenylethyl]-, 1,1-dimethylethyl ester
- Carbamic acid, N-[(1R)-2-[5-bromo-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-1-phenylethyl]-, 1,1-dimethylethyl ester
- T-BUTYL 4-BROMOBUTYRATE
- 2,2'-difluoro-3,3'-dimethoxy-1,1'-biphenyl
- Elagolix Sodium impurity4
- (R)-1,2-Diamino-1-phenylethane
- elagolix
- 1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA
- 3-Bromo-2-fluoroanisole
- (R)-2-(Boc-aMino)-2-phenylethyl 4-Methylbenzenesulfonate
- 1-[(1R)-2-hydroxy-1-phenylethyl]pyrrolidin-2-one
- Carbamic acid, N-[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-1-phenylethyl]-, 1,1-dimethylethyl ester
- 5-(2-Fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione
- 3-[(2R)-2-Amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione
- Benzeneacetic acid, 4-fluoro-.alpha.-(1-methylethyl)-, (.alpha.S)-
- Elagolix Impurity 4