Trichloroethanol Chemical Properties

Melting point:

17.8 °C (lit.)

Boiling point:

152-154 °C (lit.)

Density 

1.56 g/mL at 20 °C (lit.)

vapor density 

5.16 (vs air)

vapor pressure 

1 mm Hg ( 20 °C)

refractive index 

n20/D 1.49(lit.)

Flash point:

>230 °F

storage temp. 

Store below +30°C.

solubility 

83g/l

form 

Liquid

pka

12.24(at 25℃)

color 

Clear colorless to light yellow

Specific Gravity

1.560 (20/4℃)

Odor

ethereal odor

PH

5-6 (H2O, 20℃)(saturated solution)

Water Solubility 

Slightly soluble in water.

Sensitive 

Hygroscopic

Merck 

14,9638

BRN 

1697495

CAS DataBase Reference

115-20-8(CAS DataBase Reference)

NIST Chemistry Reference

Ethanol, 2,2,2-trichloro-(115-20-8)

EPA Substance Registry System

2,2,2-Trichloroethanol (115-20-8)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-41-67

Safety Statements 

26-39

RIDADR 

1760

WGK Germany 

1

RTECS 

KM3850000

F 

3-21

TSCA 

Yes

HazardClass 

8

PackingGroup 

III

HS Code 

29055910

Toxicity

LDLo orl-rat: 500 mg/kg CRAAA7 17,258,38

MSDS

• Language:English Provider:Trichloroethanol
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Trichloroethanol Usage And Synthesis

Chemical Properties

CLEAR COLOURLESS TO LIGHT YELLOW LIQUID

Uses

Intermediate, anesthetic.

Uses

2,2,2-Trichloroethanol (TCE) is an active metabolite of Trichloroacetaldehyde monohydrate [chloral hydrate (CH)] (T774055), a sedative/hypnotic that increases cerebral blood flow (CBF).

Uses

The 2,2,2-Trichloroethyl (TCE) moiety of 2,2,2-trichloroethanol is mainly used as a protecting group for acids, acetals and also phosphoryl groups of nucleotides. It can be easily cleaved by zinc reduction.
Some of its other application include:

• Conversion of per-O-acetylated sugars to per-O-acetylated trichloroethyl derivatives.
• Preparation of TCE ester of chlorosulfuric acid.
• Preparation of 2,2,2-trichloroethyl acetimidate hydrochloride.

Definition

ChEBI: 2,2,2-trichloroethanol is a chloroethanol. It has a role as a mouse metabolite.

Safety Profile

Poison by intravenous andintraperitoneal routes. Moderately toxic by ingestion andrectal routes. Human mutation data reported. Explosivereaction with concentrated sodium hydroxide solutions.When heated to decomposition it emits toxic fumes ofClí. Us

Trichloroethanol(115-20-8)Related Product Information

• Trichloroethylene
• Monoethanolamine
• Sucralose
• Ethanol
• 2,2-Difluoroethanol
• Trichlorosilane
• Methyl trichloroacetate
• Chlorobutanol
• 2,2,2-Trichloroethyl chloroformate
• BIS(2,2,2-TRICHLOROETHYL) PHOSPHOROCHLORIDATE
• 2,2,2-Trichloro-1-phenylethyl acetate
• METHYL 2,2,2-TRICHLOROACETIMIDATE
• 1-ethoxy-2,2,2-trichloroethano
• 2-Chloroethanol
• Trichloroacetic acid
• TRIMETHYLSILYL TRICHLOROACETATE
• Acetic acid, ester with trichloroethanol
• Chloroform