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ChemicalBook >  Product Catalog >  Analytical Chemistry >  Standard >  Pharmaceutical Impurity Reference Standards >  8-Chloro-11-(piperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine

8-Chloro-11-(piperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine

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8-Chloro-11-(piperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine Basic information

Product Name:
8-Chloro-11-(piperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine
Synonyms:
  • Dehydro Desloratadine
  • Desloratadine IMpurity C
  • Desloratadine Dehydro Impurity
  • Desloratadine Impurity 9
  • 8-Chloro-11-(4-piperidinylidene)-benzo[5,6]cyclohepta[1,2-b]pyridine
  • 8-CHLORO-11-(4-PIPERIDYLIDENE)-11H-BENZO[5,6]CYCLOHEPTA[1,2-b]PYRIDINE
  • Desloratadine dehydrogenation
  • 8-chloro-11-(piperidin-4-ylidene)
CAS:
117811-20-8
MF:
C19H17ClN2
MW:
308.8
Product Categories:
  • Amines, Aromatics, Metabolites & Impurities
  • ZY
Mol File:
117811-20-8.mol
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8-Chloro-11-(piperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine Chemical Properties

Melting point:
>163°C (dec.)
Boiling point:
477.0±45.0 °C(Predicted)
Density 
1.246±0.06 g/cm3(Predicted)
storage temp. 
Amber Vial, -20°C Freezer
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
10.21±0.20(Predicted)
form 
Solid
color 
Pale Brown
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8-Chloro-11-(piperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine Usage And Synthesis

Uses

8-Chloro-11-(piperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridineb is an impurity of Desloratadine (D290250). It was used to validate a stability-indicating ultra-performance liquid chromatography (UPLC) method for Desloratadine and its impurities in pharmaceutical dosage forms.

8-Chloro-11-(piperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridineSupplier

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8-Chloro-11-(piperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine(117811-20-8)Related Product Information