(+)-BUTACLAMOL HYDROCHLORIDE Chemical Properties

solubility 

H₂O: 0.25 mg/mL solutions should be freshly prepared.

form 

solid

color 

white

optical activity

[α]27/D +222° in methanol(lit.)

InChI

1S/C25H31NO.ClH/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25;/h4-10,21-22,27H,11-16H2,1-3H3;1H/t21-,22-,25-;/m0./s1

InChIKey

QZRUMKUMFJJARD-AAJWHBHYSA-N

SMILES

Cl[H].[H][C@@]12C[C@@](O)(CCN1C[C@@]3([H])c4ccccc4CCc5cccc2c35)C(C)(C)C

Safety Information

WGK Germany 

3

RTECS 

DE8039700

Storage Class

11 - Combustible Solids

MSDS

• Language:English Provider:SigmaAldrich

(+)-BUTACLAMOL HYDROCHLORIDE Usage And Synthesis

Uses

(+)-Butaclamol hydrochloride has been used as a dopamine receptor blocker in:

• dissected brain sections
• striatum of Parkinson′s disease specimens
• human embryonic kidney cells (HEK293 cells)
• mice striatal tissue

Biochem/physiol Actions

(+)-Butaclamol is a dopamine receptor antagonist and is an active enantiomer.

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