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TubeiMoside II

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TubeiMoside II Basic information

Product Name:
TubeiMoside II
Synonyms:
  • TubeiMoside II
  • TubeiMoside B
  • Tubeimoside Ⅱ
  • Tubeimoside BTubeimoside II
  • Tubeimoside II (Tubeimoside-B)
  • Olean-12-en-28-oicacid, 3-[[2-O-[4-O-[(3S)-4-carboxy-3-hydroxy-3-mrabinopyranosyl]-b-D-glucopyranosyl]oxy]-2,16,23-trihydroxy-,28-(O-b-D-xylopyrano
  • Tubeimoside II, BR
  • Olean-12-en-28-oicacid, 3-[[2-O-[4-O-[(3S)-4-carboxy-3-hydroxy-3-methyl-1-oxobutyl]-a-L-arabinopyranosyl]-b-D-glucopyranosyl]oxy]-2,16,23-trihydroxy-,28-(O-b-D-xylopyranosyl-(1?3)-O-6-deoxy-a-L-mannopyranosyl-(1?2)-a-L-arabinopyranosyl) ester, int
CAS:
115810-12-3
MF:
C63H98O30
MW:
1335.45
Mol File:
115810-12-3.mol
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TubeiMoside II Chemical Properties

Density 
1.53±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
2-8°C
solubility 
Soluble in DMSO and methanol;
form 
Powder
pka
12.54±0.70(Predicted)
color 
White to off-white
Water Solubility 
insoluble in water
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TubeiMoside II Usage And Synthesis

Chemical Properties

White crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Fritillaria thunbergii.

Uses

Tubeimoside II (Tubeimoside-B) is a natural analogue of oleanane type of triterpenoid saponin; show anti-inflammatory, antitumor, and antitumor-promoting effects. IC50 value: Target: The anti-inflammatory, anti-tumor, and anti-tumorigenic activities of tubeimoside II are stronger than those of tubeimoside I, and the acute toxicity of tubeimoside II is lower than that of tubeimoside I; the anti-inflammatory, anti-tumor, and anti-tumorigenic activities of tubeimoside III are stronger than those of tubeimoside II, and the acute toxicity of tubeimoside III is also stronger than that of tubeimoside II.

target

Immunology & Inflammation related

References

[1] Yu TX, et al. Structure-activity relationship of tubeimosides in anti-inflammatory, antitumor, and antitumor-promoting effects. Acta Pharmacol Sin. 2001 May;22(5):463-8. PMID:11743898

TubeiMoside IISupplier

Chengdu Biopurify Phytochemicals Ltd.
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