Basic information Safety Supplier Related

Eplerenone EP Impurity A

Basic information Safety Supplier Related

Eplerenone EP Impurity A Basic information

Product Name:
Eplerenone EP Impurity A
Synonyms:
  • Eplerenone EP Impurity A
  • Eplerenone Impurity A
  • (7α,17α)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Di-γ-lactone
  • Eplerenone Impurity 6(Eplerenone EP Impurity A)
  • Pregn-4-ene-7,21-dicarboxylic acid, 9,17-dihydroxy-3-oxo-, 7,9:21,17-dilactone, (7α,17α)-
  • (2''S)-3'',4''-Dihydro-3,5''-dioxospiro[androst-4-ene-17,2′-furan]-7α,9α-carbolactone
  • (2'R,7R,8R,9R,10S,13S,14S)-10,13-Dimethyl-7,8,11,12,13,14,15,16-octahydro-1H,3'H-spiro[9,7-(epoxymethano)cyclopenta[a]phenanthrene-17,2'-furan]-3,5',19(2H,4'H,6H,10H)-trione (Eplerenone Impurity)
  • (2'R,7R,8R,9R,10S,13S,14S)-10,13-Dimethyl-7,8,11,12,13,14,15,16-octahydro-1H,3'H-spiro[9,7-(epoxymethano)cyclopenta[a]phenanthrene-17,2'-furan]-3,5',19(2H,4'H,6H,10H)-trione (Eplerenone Impurity)
CAS:
209253-67-8
MF:
C23H28O5
MW:
384.47
Mol File:
209253-67-8.mol
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Eplerenone EP Impurity A Chemical Properties

Boiling point:
632.9±55.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
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Eplerenone EP Impurity A Usage And Synthesis

Uses

(7a,17a)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Di-γ-lactone is an eplerenone (E588775) impurity. Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.

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