Basic information Safety Supplier Related

4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one

Basic information Safety Supplier Related

4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one Basic information

Product Name:
4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one
Synonyms:
  • (R)-4-[4-[(3-Chloro-2-hydroxypropyl)amino]phenyl]morpholin-3-one
  • 4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-p ropyl)amino)phenyl]morpholin-3-one 2-[(2R)-2-hydroxy-3-{[4-(3-oxomorph olin-4-yl)phenyl]amino}propyl]-1H-is oindole-1,3(2H)-dione 2-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpho linyl)phenyl]-5-oxazolidinyl]methyl]-1H-isoindole-1
  • 3-Morpholinone, 4-[4-[[(2R)-3-chloro-2-hydroxypropyl]amino]phenyl]-
  • 1252018-10-2,4-[4-(N-(3-CHLORO-(2R)-2-HYDROXY-1-PROPYL)AMINO)PHENYL]MORPHOLIN-3-ONE
  • 4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one
CAS:
1252018-10-2
MF:
C13H17ClN2O3
MW:
284.74
Mol File:
1252018-10-2.mol
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4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one Chemical Properties

Boiling point:
604.5±55.0 °C(Predicted)
Density 
1.349±0.06 g/cm3(Predicted)
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
13.53±0.20(Predicted)
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4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one Usage And Synthesis

Uses

4-[4-[[(2R)-3-Chloro-2-hydroxypropyl]amino]phenyl]-3-morpholinone (Rivaroxaban Impurity E) is an impurity of Rivaroxaban (R538000), which is a antithrombotic agent and a FXa inhibitor.

4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-oneSupplier

Daicel Chiral Technologies (China)CO.,LTD
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Shanghai YuLue Chemical Co., Ltd.
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Shanghai AECOM Biotechnology Co. , Ltd.
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Credit Asia Chemical Co., Ltd.
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