Apixaban Impurity BMS-724914 Chemical Properties

Boiling point:

802.1±65.0 °C(Predicted)

Density 

1.39±0.1 g/cm3(Predicted)

storage temp. 

Storage temp. 2-8°C

pka

15.05±0.20(Predicted)

Appearance

Light yellow to yellow Solid

Apixaban Impurity BMS-724914 Usage And Synthesis

Uses

Des(2-oxo-1-piperidinyl) 6-(4-(5-Amino-5-oxopentyl)) Apixaban is a metabolite of Apixaban (A726700), a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.

Apixaban Impurity BMS-724914(2187409-01-2)Related Product Information

• Apixaban Impurity 34
• Butanoic acid, 2-[(4-hydroxyphenyl)hydrazono]-3-oxo-, ethyl ester
• Apixaban Related Compound 4
• ethyl 6-(4-(5-chloropentanaMido)phenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
• 1-(4-Methoxyphenyl)-6-(4-(2-Methyl-6-oxopiperidin-1-yl)phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxaMide
• Apixaban Impurity 43
• Apixaban Impurity 37
• Apixaban Impurity 30
• Apixaban Impurity 15
• Apixaban-13C-D3
• ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
• Apixaban Impurity 40
• 1-(4-(5-methyl-2-oxopiperidin-1-yl)phenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one
• Apixaban Dehydro Impurity
• Apixaban Impurity 21
• Apixaban Impurity 28
• 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-6-[4-(5-methyl-2-oxo-1-piperidinyl)phenyl]-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
• Apixaban IMpurity 5 (BMS-591329-01)