AcotiaMide
AcotiaMide Basic information
- Product Name:
- AcotiaMide
- Synonyms:
-
- AcotiaMide
- N-[2-[Bis(1-methylethyl)amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxamide
- N-(2-(diisopropylamino)ethyl)-2-(2-hydroxy-4,5-dimethoxybenzamido)thiazole-4-carboxamide hydrochloride
- ACOTIAMIDUM
- Acofide
- N-{2-[bis(1-methylethyl)amino]ethyl}-2-{[(2-hydroxy-4,5-dimethoxyphenyl)carbonyl]amino}-1,3-thiazole-4-carboxamide
- 4-Thiazolecarboxamide, N-[2-[bis(1-methylethyl)amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-
- Acotiamide formate salt
- CAS:
- 185106-16-5
- MF:
- C21H30N4O5S
- MW:
- 450.55
- Mol File:
- 185106-16-5.mol
More
Less
AcotiaMide Chemical Properties
- Density
- 1.246±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- pka
- 7.38±0.50(Predicted)
- form
- powder
- color
- white to beige
- Water Solubility
- H2O: 20mg/mL, clear
More
Less
AcotiaMide Usage And Synthesis
Definition
ChEBI: Acotiamide is a member of salicylamides.
Biological Activity
Acotiamide is a potent, selective and reversible inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide showed no affinity for dopamine D2 or serotonin 5-HT4 receptors but does have activity as a muscarinic antagonist. It acts as a prokinetic drug through acetylcholinesterase inhibition and muscarinic receptor antagonism, and has been used for the treatment of functional dyspepsia (FD) involving gastric motility dysfunction.
AcotiaMideSupplier
Adamas Reagent, Ltd.
- Tel
- 400-6009262 16621234537
- chenyj@titansci.com
Daicel Chiral Technologies (China)CO.,LTD
- Tel
- 021-50460086-9 15921403865
- han_yajun@dctc.daicel.com
T&W GROUP
- Tel
- 021-61551611 13296011611
- contact@trustwe.com
Nanjing Sunlida Biological Technology Co., Ltd.
- Tel
- 025-57798810
- sales@sunlidabio.com
Shanghai Run-Biotech Co., Ltd.
- Tel
- 021-57171705 13817537615
- sales@run-biotech.com