(αS)-3-[2-(2,6-DiMethylphenoxy)acetyl]-N-[(1S,3S,4S)-4-[[2-(2,6-diMethylphenoxy)acetyl]aMino]-3-hydroxy-5-phenyl-1-(phenylMethyl)pentyl]tetrahydro-α-(1-Methylethyl)-2-oxo-1(2H)-pyriMidineacetaMide Chemical Properties

Melting point:

>87°C (dec.)

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

Dichloromethane (Slightly), DMSO (Slightly), Methanol (Slightly)

form 

Solid

color 

White to Off-White

Stability:

Hygroscopic

(αS)-3-[2-(2,6-DiMethylphenoxy)acetyl]-N-[(1S,3S,4S)-4-[[2-(2,6-diMethylphenoxy)acetyl]aMino]-3-hydroxy-5-phenyl-1-(phenylMethyl)pentyl]tetrahydro-α-(1-Methylethyl)-2-oxo-1(2H)-pyriMidineacetaMide Usage And Synthesis

Uses

(αS)-3-[2-(2,6-Dimethylphenoxy)acetyl]-N-[(1S,3S,4S)-4-[[2-(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide (Lopinavir EP Impurity R) is an impurity of Lopinavir (L469480), a selective HIV protease inhibitor.

Uses

Impurity of Lopinavir (L469480), a selective HIV protease inhibitor.

(αS)-3-[2-(2,6-DiMethylphenoxy)acetyl]-N-[(1S,3S,4S)-4-[[2-(2,6-diMethylphenoxy)acetyl]aMino]-3-hydroxy-5-phenyl-1-(phenylMethyl)pentyl]tetrahydro-α-(1-Methylethyl)-2-oxo-1(2H)-pyriMidineacetaMide(943250-66-6)Related Product Information

• N-[(1S,2S,4S)-4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-2-(2,6-dimethylphenoxy)acetamide
• Lopinavir
• (S)-N-[(2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide
• (2,6-Xylyloxy)acetyl Lopinavir
• Lopinavir EP impurity P
• Lopinavir EP impurity Q
• Lopinavir EP impurity K
• (2S)-N-[(2S,4R,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
• Lopinavir Impurity 3
• Lopinavir Impurity 7
• Lopinavir Impurity 16
• Lopinavir Impurity 2
• Lopinavir Impurity 8
• Lopinavir Impurity 13
• Lopinavir Impurity 4
• Lopinavir Impurity 12
• Lopinavir Impurity 20
• Lopinavir Impurity 9