2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]- Chemical Properties

Melting point:

>188°C (dec.)

Boiling point:

772.6±60.0 °C(Predicted)

Density 

1.434±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

13.65±0.46(Predicted)

form 

Solid

color 

White to Off-White

Stability:

Hygroscopic

Major Application

pharmaceutical small molecule

InChI

1S/C18H20ClN3O4S/c19-16-6-5-15(27-16)18(25)21-10-14(23)9-20-12-1-3-13(4-2-12)22-7-8-26-11-17(22)24/h1-6,14,20,23H,7-11H2,(H,21,25)/t14-/m1/s1

InChIKey

OKMRQXXUAFSBCM-CQSZACIVSA-N

SMILES

[s]1c(ccc1C(=O)NC[C@H](O)CNc2ccc(cc2)N3CCOCC3=O)Cl

Safety Information

WGK Germany 

WGK 3

Storage Class

11 - Combustible Solids

2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]- Usage And Synthesis

Uses

Decarbonyl Rivaroxaban is an impurity of Rivaroxaban (R538000), which is a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.

2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]-(721401-53-2)Related Product Information

• 1,2-BenzenedicarboxaMide, N1,N2-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]-
• 4-CHLOROTHIOPHENE-2-CARBOXYLIC ACID
• 5-R-Rivaroxaban
• Rivaroxaban
• 3-Chlorothiophene-2-carboxylic acid
• Benzoic acid, 2-[[[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]aMino]carbonyl]-
• Rivaroxaban Diol (Mixture of Diastereomers)
• (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one.HCl
• 3-Morpholinone, 4-(2,4-diaMinophenyl)-
• 2,5-DICHLOROTHIOPHENE-3-CARBOXYLIC ACID
• (E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide
• Rivaroxaban Impurity 27
• Urea, N,N'-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]-
• 2-ThiophenecarboxaMide, 5-chloro-N,N-diMethyl-
• 5-Methyl-2-thiophenecarboxylic acid
• (S)-2-(3-chloro-2-hydroxypropyl)isoindoline-1,3-dione
• 2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-Morpho linyl)phenyl]aMino]propyl]-1H-isoindole-1 ,3(2H)-dione
• Rivaroxaban-d4