2-Methyl-4-nitrobenzoyl chloride Chemical Properties

Melting point:

34 °C

Boiling point:

149-153 °C(Press: 14 Torr)

Density 

1.386±0.06 g/cm3(Predicted)

storage temp. 

Room Temperature, under inert atmosphere

solubility 

Dichloromethane;

form 

Solid

color 

Pink to white

2-Methyl-4-nitrobenzoyl chloride Usage And Synthesis

Uses

2-Methyl-4-nitrobenzoyl Chloride is an intermediate in the synthesis of 7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one(C366123) ; which is an intermediate in synthesizing Tolvaptan-d7 (T536652), a labelled Tolvaptan (T536650). It is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).

2-Methyl-4-nitrobenzoyl chloride(30459-70-2)Related Product Information

• 5-Dehydro Tolvaptan
• Tolvaptan Impurity 4 (DM-4105)
• Ethyl 7-Chloro-5-oxo-1-toxyl-2,3,4,5,-tetrahydro-1H-benzo[b]azepine-4-carboxylate
• Tolvaptan Impurity 18
• Tolvaptan Impurity 13
• 5-Chloro-2-[(4-ethoxy-4-oxobutyl)[(4-methylphenyl)sulfonyl]amino]benzoic acid methyl ester
• Tolvaptan Impurity 21
• Tolvaptan Impurity 3 (DM-4104)
• Tolvaptan Impurity 30
• 7-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one
• 7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one
• Tolvaptan Impurity 17
• Tolvaptan impurity 2
• Tolvaptan Impurity 20
• Tolvaptan Impurity 15
• Tolvaptan Impurity 11
• Tolvaptan Impurity 26
• 1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one