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Ethyl 3,4-O-isopropylideneshikiMate

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Ethyl 3,4-O-isopropylideneshikiMate Basic information

Product Name:
Ethyl 3,4-O-isopropylideneshikiMate
Synonyms:
  • YDMLLAZCHMXIOO-BBBLOLIVSA-N
  • 1,3-Benzodioxole-5-carboxylic acid, 3a,6,7,7a-tetrahydro-7-hydroxy-2,2-dimethyl-, ethyl ester, (3aR,7R,7aS)-
  • Ethyl (3aR,7R,7aS)-7-hydroxy-2,2-dimethyl-3a,6,7,7a-tetrahydrobenzo[d][1,3]dioxole-5-carboxylate (Oseltamivir Impurity)
  • Oseltamivir?Impurity?55/Ethyl?(3aR,7R,7aS)-7-hydroxy-2,2-dimethyl-3a,6,7,7a-tetrahydrobenzo[d][1,3]dioxole-5-carboxylate
  • Ethyl 3,4-O-isopropylideneshikimate
CAS:
136994-78-0
MF:
C12H18O5
MW:
242.27
Mol File:
136994-78-0.mol
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Ethyl 3,4-O-isopropylideneshikiMate Chemical Properties

Melting point:
55-58°C
Boiling point:
356.6±42.0 °C(Predicted)
Density 
1.190±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Solid
pka
13.40±0.60(Predicted)
color 
White to Pale Yellow
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Ethyl 3,4-O-isopropylideneshikiMate Usage And Synthesis

Uses

Ethyl 3,4-O-isopropylideneshikimate is an acetonide used in the synthesis of Oseltamivir phosphate (O701000), an orally active inhibitor of influenza virus neuraminidase; converted in vivo to the active acid metabolite. An antiviral drug.

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