2,6-Naphthalenediol Chemical Properties

Melting point:

223-225 °C(lit.)

Boiling point:

246.06°C (rough estimate)

Density 

1.0924 (rough estimate)

refractive index 

1.5418 (estimate)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

9.55±0.40(Predicted)

color 

White to Off-White

Water Solubility 

Soluble in methanol and hot water. Slightly soluble in water.

BRN 

1238082

CAS DataBase Reference

581-43-1(CAS DataBase Reference)

NIST Chemistry Reference

2,6-Dihydroxynaphthalene(581-43-1)

EPA Substance Registry System

2,6-Naphthalenediol (581-43-1)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

WGK Germany 

2

F 

10-23

TSCA 

Yes

HS Code 

29309090

MSDS

• Language:English Provider:2,6-Dihydroxynaphthalene
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2,6-Naphthalenediol Usage And Synthesis

Uses

2,6-Dihydroxynaphthalene is used in the preparation of 1,5-dichloro-2,6-diethynylnaphthalenes. It is used to produce convulsions in mice. It exhibits antiproliferative activity towards certain cells. It is also employed in the preparation of the first-generation rotaxane dendrimer. Further, it is used in the production of several dyes, pigments, fluorescent whiteners, tanning agents, antioxidants and antiseptics. In addition to this, it is converted into amines, esters, ethers and carboxylic derivatives.

Synthesis

2,6-Naphthalenediol [581-43-1], 2,6- naphthohydroquinone, mp 222℃, is synthesized by potassium hydroxide fusion of 2-hydroxynaphthalene-6-sulfonic acid at 295℃. It undergoes amination at 250℃ to give 2,6-naphthalenediamine and couples with diazotized anilines in the 1-position under acid conditions or the 1,5- positions under alkaline conditions.

2,6-Naphthalenediol (581-43-1)Related Product Information

• Butylated Hydroxytoluene
• N-(1-Naphthyl)ethylenediamine dihydrochloride
• 1,3-DINITRONAPHTHALENE
• Perylene
• Naphthalene
• Triclosan
• 1,3-Dihydroxyacetone
• 2,6-DIMETHYLNAPHTHALENE
• 1-Hydroxyethylidene-1,1-diphosphonic acid
• 2-Naphthol
• Chrysin
• 3-Diethylaminophenol
• 1,3-DIHYDROXYNAPHTHALENE
• 3,7-Dihydroxy-2-naphthoic acid
• 7-Hydroxyaristolochic acid A
• 6-Methoxy-2-naphthol
• 2,6-Naphthalenediol diacetate
• 2,6-Dimethoxynaphthalene