Evolocumab
Evolocumab Basic information
- Product Name:
- Evolocumab
- Synonyms:
-
- Evolocumab
- AMG 145
- Research Grade Evolocumab(DHJ24002)
- AMG-145,Ser/Thr Protease,Repatha,AMG 145,inhibit,atherosclerotic cardiovascular disease,Serine endopeptidases,PCSK9,Evolocumab,AMG145,Threonine proteases,hypercholesterolemia,LDLR,Inhibitor,Serine proteases
- Evolocumab(anti-PCSK9)
- CAS:
- 1256937-27-5
- MW:
- 0
- Mol File:
- Mol File
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Evolocumab Chemical Properties
- storage temp.
- Store at 4°C, protect from light
- form
- Liquid
- color
- Colorless to light yellow
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Safety Information
- Hazardous Substances Data
- 1256937-27-5(Hazardous Substances Data)
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Evolocumab Usage And Synthesis
Clinical Use
IgG2 monoclonal antibody:Treatment of hypercholesterolaemia, mixed dyslipidaemia and homozygous familial hypercholesterolaemia
Drug interactions
Potentially hazardous interactions with other drugs Antipsychotics: avoid with clozapine - increased risk of agranulocytosis. Vaccines: avoid concomitant use with live vaccines.
Metabolism
Evolocumab is composed of amino acids and carbohydrates as native immunoglobulin and is unlikely to be eliminated via hepatic metabolic mechanisms. Its metabolism and elimination are expected to follow the immunoglobulin clearance pathways, resulting in degradation to small peptides and individual amino acids.
EvolocumabSupplier
Wuhan Sunrise Technology Development Co., Ltd.
- Tel
- 27-027-83314682 13554138826
- whsrtech@vip.163.com
Wuhan Fortuna Chemical Co., Ltd
- Tel
- 027-59207852 13308628970
- buy@fortunachem.com
Dalian Meilun Biotech Co., Ltd.
- Tel
- 0411-62910999 13889544652
- meilunui@163.com
Nanjing Sunlida Biological Technology Co., Ltd.
- Tel
- 025-57798810
- sales@sunlidabio.com
Sichuan Wei Keqi Biological Technology Co., Ltd.
- Tel
- 028-81700200 18116577057
- 3003855609@qq.com