Basic information Safety Supplier Related

N-(2-Aminoethyl)piperidine

Basic information Safety Supplier Related

N-(2-Aminoethyl)piperidine Basic information

Product Name:
N-(2-Aminoethyl)piperidine
Synonyms:
  • 2-(1-Piperidinyl)ethanamine
  • 2-(1-Piperidinyl)ethylamine
  • Piperidine, 1-(2-aminoethyl)-
  • LABOTEST-BB LT02100617
  • 1-PIPERIDINE ETHYLAMINE
  • 2-(1-PIPERIDINO)ETHYLAMINE
  • 2-PIPERIDINOETHYLAMINE
  • 2-PIPERIDIN-1-YL-ETHYLAMINE
CAS:
27578-60-5
MF:
C7H16N2
MW:
128.22
EINECS:
248-540-8
Product Categories:
  • API intermediates
Mol File:
27578-60-5.mol
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N-(2-Aminoethyl)piperidine Chemical Properties

Melting point:
67-70 °C(Solv: ligroine (8032-32-4); dichloromethane (75-09-2))
Boiling point:
186 °C(lit.)
Density 
0.899 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.473(lit.)
Flash point:
136 °F
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
Liquid
pka
pK1: 6.38;pK2: 9.89 (30°C)
color 
Clear colorless to yellow
Water Solubility 
Partly miscible in water.
Sensitive 
Air Sensitive
BRN 
103469
CAS DataBase Reference
27578-60-5(CAS DataBase Reference)
NIST Chemistry Reference
1-Piperidineethanamine(27578-60-5)
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Safety Information

Hazard Codes 
C,Xi
Risk Statements 
34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 2734 8/PG 2
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
3
PackingGroup 
III
HS Code 
29333990

MSDS

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N-(2-Aminoethyl)piperidine Usage And Synthesis

Chemical Properties

CLEAR COLOURLESS TO YELLOW LIQUID

Uses

1-(2-Aminoethyl)piperidine is used in modification of vinylbenzyl chloride/divinylbenzene gel copolymer bead and in the synthesis of linkage isomers trans-bis[1-(2-aminoethyl)piperidine]dinitronickel and trans-bis[1-(2-aminoethyl)-piperidine]dinitritonickel. It is also used as a reactant for synthesis of: analogs of anticancer agents, inhibitor of botulinum neurotoxin serotype A light chain, P. falciparum malaria, and Ebola filovirus, cannabinoid CB1 receptor antagonists, small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells, potent and selective 5-HT6 antagonists and N-mustards as anticancer agents. 1-(2-Aminoethyl)piperidine on [1+1] condensation reaction with 3-methoxy salicylaldehyde yields tridentate Schiff base ligand.

General Description

1-(2-Aminoethyl)piperidine on [1+1] condensation reaction with 3-methoxy salicylaldehyde yields tridentate Schiff base ligand.

N-(2-Aminoethyl)piperidine Preparation Products And Raw materials

Raw materials

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