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2,4-Dichloro-6,7-dimethoxyquinazoline

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2,4-Dichloro-6,7-dimethoxyquinazoline Basic information

Product Name:
2,4-Dichloro-6,7-dimethoxyquinazoline
Synonyms:
  • TIMTEC-BB SBB000972
  • 2,4-DICHLORO-6,7-DIMETHOXYQUINAZOLINE
  • 2,4-Dichloro-6,7-dimethoxyquin
  • Doxazosin Impurity 5(Doxazosin EP Impurity E)
  • Doxazosin Impurity 6
  • 2-Chloro-6,7-diMethoxyquinazolin-4-yl Chloride
  • 2,4-Dichloro-6-Methoxy-7-quinazolinyl Methyl ether
  • Doxazosin Related Compound E (20 mg) (2,4-dichloro-6,7-dimethoxyquinazoline)
CAS:
27631-29-4
MF:
C10H8Cl2N2O2
MW:
259.09
EINECS:
608-117-4
Product Categories:
  • Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Quinazolines
  • QuinazolinesHeterocyclic Building Blocks
  • Aromatics
  • Heterocycles series
  • Quinolines, Quinazolines and derivatives
  • Quinoline&Isoquinoline
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
27631-29-4.mol
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2,4-Dichloro-6,7-dimethoxyquinazoline Chemical Properties

Melting point:
175-178 °C (lit.)
Boiling point:
340.5±42.0 °C(Predicted)
Density 
1.5369 (rough estimate)
refractive index 
1.6100 (estimate)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
-0.49±0.30(Predicted)
form 
Crystalline Powder
color 
Pale yellow to beige
Water Solubility 
Insoluble in water.
Sensitive 
Moisture Sensitive
BRN 
190331
CAS DataBase Reference
27631-29-4(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26-36
WGK Germany 
3
HS Code 
29334900

MSDS

  • Language:English Provider:ACROS
  • Language:English Provider:ALFA
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2,4-Dichloro-6,7-dimethoxyquinazoline Usage And Synthesis

Chemical Properties

pale yellow to beige crystalline powder

Uses

An intermediate in the preparation of potential inhibitors of epidermal growth factor receptor kinases. An intermediate in the preparation of Terazosin (T105000).

Uses

2,4-Dichloro-6,7-dimethoxyquinazoline is used as an intermediate in the preparation of potential inhibitors of epidermal growth factor receptor kinases. It is also used as an intermediate in the preparation of terazosin.

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