Anti-Protein phosphatase 1
Anti-Protein phosphatase 1 Basic information
- Product Name:
- Anti-Protein phosphatase 1
- Synonyms:
-
- Anti-GADD34
- Anti-Growth arrest and DNA-damage-inducible 34
- Anti-PPP1R15A/GADD34 antibody produced in goat
- Anti-Protein phosphatase 1
- MW:
- 0
- Mol File:
- Mol File
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Anti-Protein phosphatase 1 Chemical Properties
- storage temp.
- -20°C
- form
- buffered aqueous solution
- biological source
- goat
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Anti-Protein phosphatase 1 Usage And Synthesis
Biological Activity
Protein phosphatase 1 regulatory subunit 15A (PPP1R15A) recruits and regulates the α-subunit of protein phosphatase 1 (PP1). It functions as a stress marker. When there is depletion in amino acid levels in the cell, PPP1R15A is expressed in high concentrations. It regulates the mammalian target of rapamycin (mTOR) pathway and thereby boosts autophagy in macrophages. Studies have shown th at PPP1R15A is expressed in the oligodendrocytes of patients suffering from Alzheimer′s disease.