4-Amino-3,5-diiodobenzoic acid Chemical Properties

Melting point:

>300 °C(lit.)

Boiling point:

448.7±45.0 °C(Predicted)

Density 

2.3815 (estimate)

storage temp. 

2-8°C

pka

4.16±0.10(Predicted)

Water Solubility 

Soluble in water (partly miscible).

Sensitive 

Light Sensitive

BRN 

2103037

CAS DataBase Reference

2122-61-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-22

Safety Statements 

26-37/39-36/37/39

WGK Germany 

3

RTECS 

DG2310000

HS Code 

29224985

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

4-Amino-3,5-diiodobenzoic acid Usage And Synthesis

Chemical Properties

beige-pink crystalline powder

Uses

4-Amino-3,5-diiodobenzoic acid is a very useful substituted benzene compound for use as a building block in synthesis. The carboxylic acid and amine functionalities can be used to form linkages through nucleophile-electrophile coupling and the iodides may be used as functional sites for cross-coupling transformations. 4-Amino-3,5-diiodobenzoic acid has been specifically used in the synthesis of an adduct to introduce into Tecoflex polymers to impart radiopaqueness to the material.

Purification Methods

Purify the iodo-acid by dissolving it in dilute NaOH and precipitating with dilute HCl. Alternatively, dissolve it in aqueous NH3 and acidify it with AcOH. Dry it in air. The solubility of the Na salt in H2O is 2.56% at 25o. [Klemme & Hunter J Org Chem 5 510 1940, Beilstein 14 H 439, 14 III 1161, 14 IV 1284.]

4-Amino-3,5-diiodobenzoic acid(2122-61-4)Related Product Information

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• 2-AMINO-3,5-DIIODOBENZOIC ACID,2-Amino-3,5-diiodobenzoic acid, 98+%