1-(2-Aminoethyl)pyrrolidine Chemical Properties

Melting point:

219 °C (decomp)

Boiling point:

66-70 °C/23 mmHg (lit.)

Density 

0.901 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.468(lit.)

Flash point:

118 °F

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

pka

pK1: 6.56(+2);pK2: 9.74(+1)(30°C)

form 

Liquid

Specific Gravity

0.901

color 

Clear colorless to light brown

Sensitive 

Air Sensitive

BRN 

102978

InChI

1S/C6H14N2/c7-3-6-8-4-1-2-5-8/h1-7H2

InChIKey

WRXNJTBODVGDRY-UHFFFAOYSA-N

SMILES

NCCN1CCCC1

CAS DataBase Reference

7154-73-6(CAS DataBase Reference)

NIST Chemistry Reference

1-Pyrrolidineethanamine(7154-73-6)

EPA Substance Registry System

1-Pyrrolidineethanamine (7154-73-6)

Safety Information

Hazard Codes 

C

Risk Statements 

10-34

Safety Statements 

16-26-27-36/37/39-45

RIDADR 

UN 2734 8/PG 2

WGK Germany 

3

F 

9-23

TSCA 

TSCA listed

HazardClass 

3

PackingGroup 

III

HS Code 

29339900

Storage Class

3 - Flammable liquids

Hazard Classifications

Flam. Liq. 3
Skin Corr. 1B

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

1-(2-Aminoethyl)pyrrolidine Usage And Synthesis

Chemical Properties

CLEAR COLORLESS TO LIGHT BROWN LIQUID

Uses

1-(2-Aminoethyl)pyrrolidine may be used in the preparation of one-dimensional coordination polymer of nickel(II), [(μ_N,S-NCS)₂{Ni(ampy)}]n (ampy=1-(2-aminoethyl)pyrrolidine).

General Description

1-(2-Aminoethyl)pyrrolidine is a heterocyclic building block. Nickel(II) salts of 1-(2-aminoethyl)pyrrolidine have been synthesized and thermal studies have been reported. The isomeric complexes trans-[NiL₂(NCS)₂] (violet) and cis-[NiL₂(NCS)₂] (blue) [L=1-(2-aminoethyl)pyrrolidine] have been synthesized and their X-ray crystal structure have been studied.

Synthesis

Add (1-pyrrole) acetonitrile, Raney nickel and methanol (400 mL) in a 1L hydrogenation kettle. Inert the hydrogenation kettle, control the internal temperature of 20-30 ??, continuous through the hydrogen to maintain the pressure of 0.4-0.5 MPa, hydrogenation reaction until the hydrogen is not consumed. Hydrogenation is completed, filtration, and methanol (50 ml * 2) wash, collect the filtrate and wash. The residue was concentrated to dryness by distillation under reduced pressure. Then distillation under reduced pressure, collect (boiling point: 100-105 ?? / 60mmHg) fraction, obtained colorless liquid 1-(2-aminoethyl)pyrrolidine 35.9 g, yield 85.5%, purity 99.0% (GC).

1-(2-Aminoethyl)pyrrolidine(7154-73-6)Related Product Information

• Pyrrolidine
• Polyvinylpyrrolidone
• N-(2-Hydroxyethyl)pyrrolidine
• 2-(2-Aminoethylamino)ethanol
• N-Methyl-2-pyrrolidone
• 1-Methylpyrrolidine
• Povidone iodine
• N-Vinyl-2-pyrrolidone
• METHYL-2-PYRROLIDONE
• (S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine
• GLYCYL-L-PROLINE
• Actinomycin D
• 1-((PYRROLIDINE-1-CARBONYL)METHYL)PIPERAZINE
• Z-GLY-PRO-OH
• L-Alanyl-L-proline
• N-Ethyl-2-Aminoethyl Pyrrolidine
• N-methyl-2-(2-aminoethyl)pyrrolidine,1-methyl-2-(aminoethyl)pyrrolidine,N-Methyl-(2-aminoethyl)-pyrrolidine,1-METHYL-2-(2-AMINOETHYL)PYRROLIDINE
• Z-ALA-PRO-OH