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Guanidineacetic acid

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Guanidineacetic acid Basic information

Product Name:
Guanidineacetic acid
Synonyms:
  • N-Amidinoglycin
  • (Aminoiminomethyl)aminoacetic acid
  • GLYCOCYAMINE(GUANIDINOACETIC ACID)(P)
  • Guanidineacetic acid,N-Amidinoglycine, N-Guanylglycine, Glycocyamine
  • Guanidineacetic acid 99%
  • Guanidineacetic acid,glucocyamine,Glycocyamine
  • BetacyaMine
  • NSC 1901
CAS:
352-97-6
MF:
C3H7N3O2
MW:
117.11
EINECS:
206-529-5
Product Categories:
  • Pharmaceutical Intermediates
  • Amino acids
  • Building Blocks
  • Chemical Synthesis
  • Guanidines
  • Nitrogen Compounds
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Organic Building Blocks
  • 352-97-6
Mol File:
352-97-6.mol
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Guanidineacetic acid Chemical Properties

Melting point:
300 °C(lit.)
Boiling point:
218.88°C (rough estimate)
Density 
1.4020 (rough estimate)
refractive index 
1.4900 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
6 M NaOH : 50 mg/mL, clear, colorless
pka
2.82(at 25℃)
form 
Solid
color 
White to Off-White
Water Solubility 
3.6g/L(15 ºC)
Merck 
14,4495
BRN 
1759179
InChIKey
BPMFZUMJYQTVII-UHFFFAOYSA-N
CAS DataBase Reference
352-97-6(CAS DataBase Reference)
EPA Substance Registry System
Glycocyamine (352-97-6)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
MB7700000
HS Code 
29252000

MSDS

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Guanidineacetic acid Usage And Synthesis

Chemical Properties

WHITE TO SLIGHTLY BEIGE FINE CRYSTALLINE POWDER

Uses

Guanidinoacetic Acid is an important marker for renal failure, in kidney transplantation, and for the renal metabolic activity.

Definition

ChEBI: The N-amidino derivative of glycine.

Purification Methods

Recrystallise it from 15 parts of hot H2O, or by dissolving it in slightly more than the calculated amount of 2N HCl and precipitating it by adding an equivalent of 2N NaOH, filtering, washing with cold H2O and drying first in vacuo, then at 60o in vacuo. The hydrochloride has m 200o(dec) after recrystallisation from aqueous HCl as plates. The picrate forms needles from hot H2O with m 210o(dec). [Brand & Brand Org Synth Coll Vol III 440 1955, Failey & Brand J Biol Chem 102 768 1933, King J Chem Soc 2375 1930, Beilstein 4 H 359, 4 I 477, 4 II 793, 4 III 1165.]

Guanidineacetic acid Preparation Products And Raw materials

Raw materials

Guanidineacetic acidSupplier

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