Guanidineacetic acid Chemical Properties

Melting point:

300 °C(lit.)

Boiling point:

218.88°C (rough estimate)

Density 

1.4020 (rough estimate)

refractive index 

1.4900 (estimate)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

6 M NaOH : 50 mg/mL, clear, colorless

pka

2.82(at 25℃)

form 

Solid

color 

White to Off-White

Water Solubility 

3.6g/L(15 ºC)

Merck 

14,4495

BRN 

1759179

InChI

1S/C3H7N3O2/c4-3(5)6-1-2(7)8/h1H2,(H,7,8)(H4,4,5,6)

InChIKey

BPMFZUMJYQTVII-UHFFFAOYSA-N

SMILES

NC(=N)NCC(O)=O

CAS DataBase Reference

352-97-6(CAS DataBase Reference)

EPA Substance Registry System

Glycocyamine (352-97-6)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

MB7700000

HS Code 

29252000

Storage Class

11 - Combustible Solids

MSDS

• Language:English Provider:Guanidineacetic acid
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Guanidineacetic acid Usage And Synthesis

Chemical Properties

WHITE TO SLIGHTLY BEIGE FINE CRYSTALLINE POWDER

Uses

Guanidinoacetic Acid is an important marker for renal failure, in kidney transplantation, and for the renal metabolic activity.

Definition

ChEBI: The N-amidino derivative of glycine.

Purification Methods

Recrystallise it from 15 parts of hot H2O, or by dissolving it in slightly more than the calculated amount of 2N HCl and precipitating it by adding an equivalent of 2N NaOH, filtering, washing with cold H2O and drying first in vacuo, then at 60o in vacuo. The hydrochloride has m 200o(dec) after recrystallisation from aqueous HCl as plates. The picrate forms needles from hot H2O with m 210o(dec). [Brand & Brand Org Synth Coll Vol III 440 1955, Failey & Brand J Biol Chem 102 768 1933, King J Chem Soc 2375 1930, Beilstein 4 H 359, 4 I 477, 4 II 793, 4 III 1165.]

Guanidineacetic acid(352-97-6)Related Product Information

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