Acetyl tetrapeptide-3 Chemical Properties

Boiling point:

1075.4±65.0 °C(Predicted)

Density 

1.250±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

solubility 

DMF: 14 mg/ml DMSO: 10 mg/ml Ethanol: 10 mg/ml PBS (pH 7.2): 10 mg/ml

pka

13.35±0.46(Predicted)

form 

A solid

InChI

InChI=1S/C22H39N9O5/c1-14(32)29-17(7-3-5-9-24)21(35)27-12-19(33)30-18(10-15-11-26-13-28-15)22(36)31-16(20(25)34)6-2-4-8-23/h11,13,16-18H,2-10,12,23-24H2,1H3,(H2,25,34)(H,26,28)(H,27,35)(H,29,32)(H,30,33)(H,31,36)/t16-,17-,18-/m0/s1

InChIKey

RRJOMESUBQAYOA-BZSNNMDCSA-N

SMILES

C(N)(=O)[C@H](CCCCN)NC(=O)[C@H](CC1N=CNC=1)NC(=O)CNC(=O)[C@H](CCCCN)NC(C)=O

Acetyl tetrapeptide-3 Usage And Synthesis

Description

Acetyl tetrapeptide-3 is a biomimetic peptide. It increases protein levels of type III collagen and total laminins in MRC5 human fibroblasts when used at a concentration of 1 μM. Acetyl tetrapeptide-3 reverses corticoid-induced decreases in collagen VII expression at the dermal-epidermal junction in human skin explants.

Uses

Acetyl tetrapeptide-3 stimulates hair growth with higher activity than the reference hair growth product, Minoxidil. This can help to anchor the hair fibre into the scalp which can strengthen strands and target the causes of hair loss. By combining this ingredient with Red Clover Extract, the benefits can be accelerated helping to improve blood circulation to the roots, increasing thickness and hair volume.

benefits

Acetyl Tetrapeptide-3 Stimulate fibroblast around dermal follicle toproduce matrix protein( collagen lll, laminin.etc.)and collagen VlI, fill the hair follicle, boost hairgrowth. Its recommended dosage is 1~5%.

Biological Functions

Acetyl tetrapeptide-3 is a biomimetic peptide. It increases protein levels of type III collagen and total laminins in MRC5 human fibroblasts when used at a concentration of 1 μM. Acetyl tetrapeptide-3 reverses corticoid-induced decreases in collagen VII expression at the dermal-epidermal junction in human skin explants.

Acetyl tetrapeptide-3(827306-88-7)Related Product Information

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• Octapeptide 2
• Acetyl Tetrapeptide-5
• Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide
• Palmitoyl Hexapeptide-12
• Tripeptide-1
• TYR-D-ALA-GLY-PHE-LEU
• (2S)-N2-(1-Oxohexadecyl)-L-lysyl-L-valyl-2,4-diaminobutanoic acid bis(trifluoroacetate)
• Acetyl Dipeptide-1 cetyl ester
• MET-GLU-HIS-PHE-ARG-TRP-GLY
• H-VAL-TRP-OH
• Rigin
• Biotinoyl tripeptide-1
• Copper Peptide
• L-Carnosine
• Acetyl Tetrapeptide-9
• Acetyl hexapeptide 38
• Hexapeptide 9