Basic information Safety Supplier Related

Biotin-PEG3-Mal

Basic information Safety Supplier Related

Biotin-PEG3-Mal Basic information

Product Name:
Biotin-PEG3-Mal
Synonyms:
  • Biotin-PEG3-Mal
  • (+)-Biotin-PEG3-NH-Mal
  • Biotin Impurity 29
  • Biotin-dPEG??-MAL
  • (+)-Biotin-PEG3-Maleimide
  • Biotin-PEG3-amido-Mal
  • Biotin-PEG4-BMPA
  • 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-13-oxo-3,6,9-trioxa-12-azapentadec-1-yl]hexahydro-2-oxo-, (3aS,4S,6aR)-
CAS:
1431618-70-0
MF:
C25H39N5O8S
MW:
569.67
Product Categories:
  • peg
  • SiChem
Mol File:
1431618-70-0.mol
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Biotin-PEG3-Mal Chemical Properties

Boiling point:
905.9±65.0 °C(Predicted)
Density 
1.258±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
solubility 
Soluble in DMSO, DCM, DMF
form 
Solid
pka
13.90±0.40(Predicted)
color 
White to off-white
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Safety Information

HS Code 
2942000090
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Biotin-PEG3-Mal Usage And Synthesis

Description

Biotin-PEG3-Mal is a maleimide Biotinylation reagent that can react with sulfhydryl groups (at pH 6.5-7.5) specifically to form a thioether linkage.

Uses

Biotin-PEG3-Mal is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329

Biotin-PEG3-MalSupplier

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Biotin-PEG3-Mal(1431618-70-0)Related Product Information